SCHEMBL3546170

SCHEMBL3546170

OC1CCC(C2CCC3OC3C2)CC1

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
GMNN O75496 1/20 0.31
LMNA P02545 1/20 0.31
PMP22 Q01453 1/20 0.31
TFPI2 P48307 1/20 0.31
TP53 P04637 1/20 0.31
TSHR P16473 1/20 0.31
NFKB1 P19838 1/20 0.31
THPO P40225 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9924687 0.87 TFPI2 (0.32) KDM4EGMNNLMNAPMP22TFPI2
SCHEMBL3544743 0.87
SCHEMBL3544745 0.85 PTGS1 (0.32)
SCHEMBL13484113 0.85
SCHEMBL14510049 0.84 TFPI2 (0.33) KDM4EGMNNLMNAPMP22TFPI2
SCHEMBL13784893 0.84 TFPI2 (0.33) KDM4EGMNNLMNAPMP22TFPI2
SCHEMBL15813209 0.84 TFPI2 (0.33) KDM4EGMNNLMNAPMP22TFPI2
SCHEMBL658709 0.84 TFPI2 (0.33) KDM4EGMNNLMNAPMP22TFPI2
SCHEMBL15980921 0.84 TFPI2 (0.33) KDM4EGMNNLMNAPMP22TFPI2
SCHEMBL15765562 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3095833-B1 NEMATIC LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY DEVICE USING SAME DAINIPPON INK & CHEMICALS (JP) 2018-06-27 EP disclosed
US-20170349779-A1 ANTI-WEAR AGENT DAICEL CORPORATION (JP) 2017-12-07 US disclosed
US-20170298198-A1 AROMATIC POLYAMIDE FILMS FOR SOLVENT RESISTANT FLEXIBLE SUBSTRATES SUMITOMO BAKELITE CO., LTD. (JP) 2017-10-19 US disclosed
EP-2883935-B1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING SAME DAINIPPON INK & CHEMICALS (JP) 2017-08-30 EP disclosed
EP-2762548-B1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DAINIPPON INK & CHEMICALS (JP) 2017-03-29 EP disclosed
US-20160186684-A1 SLIDING MEMBER AND METHOD OF MANUFACTURING THE SAME TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2016-06-30 US disclosed
US-20150232697-A1 SOLUTION OF AROMATIC POLYAMIDE FOR PRODUCING DISPLAY ELEMENT, OPTICAL ELEMENT, ILLUMINATION ELEMENT OR SENSOR ELEMENT AKRON POLYMER SYSTEMS, INC. (US) 2015-08-20 US disclosed
WO-2014105890-A1 AROMATIC POLYAMIDE FILMS FOR SOLVENT RESISTANT FLEXIBLE SUBSTRATES AKRON POLYMER SYSTEMS, INC. (US) 2014-07-03 WO disclosed
US-7732627-B2 High-purity cycloaliphatic diepoxy compound and preparation process thereof DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2010-06-08 US disclosed
US-20080045729-A1 High-Purity Cycloaliphatic Diepoxy Compound and Preparation Process Thereof DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2008-02-21 US disclosed
EP-1834949-A1 HIGH-PURITY ALICYCLIC DIEPOXY COMPOUND AND PROCESS FOR PRODUCING THE SAME Daicel Chemical Industries, Ltd. (JP) 2007-09-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080045729-A1 High-Purity Cycloaliphatic Diepoxy Compound and Preparation Process Thereof DUOX2, SQLE, HPD KDM4E 3356/4885GMNN 2978/4885LMNA 4735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.