Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19500885 | 0.88 | SMN1; SMN2 (0.36) | SMN1; SMN2NOS1FDPSESR2HSD17B10 | |
| SCHEMBL26078424 | 0.85 | KDM4E (0.37) | SMN1; SMN2NOS1ESR2HSD17B10L3MBTL1 | |
| SCHEMBL26350953 | 0.83 | SMN1; SMN2 (0.39) | SMN1; SMN2NOS1FDPSESR2HSD17B10 | |
| SCHEMBL14234083 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2NOS1FDPSESR2HSD17B10 | |
| SCHEMBL13103844 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2NOS1FDPSESR2HSD17B10 | |
| SCHEMBL10192297 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2NOS1FDPSESR2HSD17B10 | |
| SCHEMBL24919807 | 0.77 | SMN1; SMN2 (0.34) | SMN1; SMN2NOS1ESR2HSD17B10L3MBTL1 | |
| SCHEMBL27819802 | 0.75 | SMN1; SMN2 (0.35) | SMN1; SMN2NOS1ESR2HSD17B10L3MBTL1 | |
| SCHEMBL27819816 | 0.75 | SMN1; SMN2 (0.35) | SMN1; SMN2NOS1ESR2HSD17B10L3MBTL1 | |
| SCHEMBL21011913 | 0.74 | SMN1; SMN2 (0.38) | SMN1; SMN2NOS1FDPSESR2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11330821-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2022-05-17 | — | — | US | disclosed |
| US-10292394-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2019-05-21 | — | — | US | disclosed |
| US-20180116219-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-03 | — | — | US | disclosed |
| US-20180110225-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-26 | — | — | US | disclosed |
| US-8163746-B2 | Azolecarboxamide derivative | ASTELLAS PHARMA INC. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11330821-B2 | Herbicidal compounds | DDT, HPD, HDHD5 | SMN1; SMN2 4792/4885NOS1 3304/4885FDPS 361/4885 |
| US-20180110225-A1 | HERBICIDAL COMPOUNDS | DDT, HPD, DDC | SMN1; SMN2 4832/4885NOS1 2650/4885FDPS 195/4885 |
| US-20180116219-A1 | HERBICIDAL COMPOUNDS | DDT, HPD, HDHD5 | SMN1; SMN2 4792/4885NOS1 3304/4885FDPS 361/4885 |
| US-10292394-B2 | Herbicidal compounds | DDT, HPD, DDC | SMN1; SMN2 4832/4885NOS1 2650/4885FDPS 195/4885 |
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | GPR17, NTRK1, TRPV1 | SMN1; SMN2 3601/4885NOS1 1900/4885FDPS 2976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.