Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | NNMT | P40261 | 2/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | OXTR | P30559 | 2/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3554154 | 0.91 | KMT2A (0.46) | KMT2AALDH1A1POLBNNMTCHRNA7 | |
| SCHEMBL10318613 | 0.84 | NPSR1 (0.49) | KMT2AALDH1A1POLBNNMTCHRNA7 | |
| SCHEMBL6069865 | 0.84 | PTGS2 (0.49) | KMT2AALDH1A1POLBNNMTCHRNA7 | |
| SCHEMBL6069855 | 0.84 | PTGS2 (0.49) | KMT2AALDH1A1POLBNNMTCHRNA7 | |
| SCHEMBL10317483 | 0.84 | NPSR1 (0.49) | KMT2AALDH1A1POLBNNMTCHRNA7 | |
| SCHEMBL2388678 | 0.83 | NNMT (0.47) | KMT2AALDH1A1POLBNNMTCHRNA7 | |
| SCHEMBL7014236 | 0.79 | NNMT (0.47) | KMT2AALDH1A1POLBNNMTCHRNA7 | |
| SCHEMBL7082182 | 0.79 | NNMT (0.47) | KMT2AALDH1A1POLBNNMTCHRNA7 | |
| SCHEMBL7083560 | 0.79 | NNMT (0.47) | KMT2AALDH1A1POLBNNMTCHRNA7 | |
| SCHEMBL6221566 | 0.78 | ITGB3 (0.50) | KMT2AALDH1A1POLBNNMTCHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7727998-B2 | Melanin-concentrating hormone receptor antagonists containing piperidine derivatives as the active ingredient | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-06-01 | — | — | US | disclosed |
| US-20060106046-A1 | Melanin-concentrating hormone receptor antagonists containing piperidine derivatives as the active ingredient | MSD K.K. (JP) | 2006-05-18 | — | — | US | disclosed |
| EP-1595867-A1 | MELANIN-CONCENTRATING HORMONE RECEPTOR ANTAGONISTS CONTAINING PIPERIDINE DERIVATIVES AS THE ACTIVE INGREDIENT | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-11-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106046-A1 | Melanin-concentrating hormone receptor antagonists containing piperidine derivatives as the active ingredient | MCHR1, MC1R, PRLHR | KMT2A 1378/4885ALDH1A1 953/4885POLB 2699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.