Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.71 |
| ▸ | ALDH1A3 | P47895 | 6/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4079761 | 0.83 | ALDH1A1 (1.00) | ALDH1A1ALDH1A3SMN1; SMN2HTTMEN1 | |
| SCHEMBL15339337 | 0.82 | ALDH1A3 (1.00) | ALDH1A1ALDH1A3SMN1; SMN2HTTMEN1 | |
| SCHEMBL2557677 | 0.81 | ALDH1A1 (0.62) | ALDH1A1ALDH1A3SMN1; SMN2HTTMEN1 | |
| SCHEMBL16464268 | 0.79 | ALDH1A1 (0.73) | ALDH1A1ALDH1A3SMN1; SMN2HTTMEN1 | |
| SCHEMBL2557270 | 0.79 | ALDH1A1 (0.59) | ALDH1A1ALDH1A3SMN1; SMN2HTTMEN1 | |
| SCHEMBL2561170 | 0.79 | ALDH1A3 (0.59) | ALDH1A1ALDH1A3SMN1; SMN2HTTMEN1 | |
| SCHEMBL4941255 | 0.79 | ALDH1A1 (0.68) | ALDH1A1ALDH1A3SMN1; SMN2HTTMEN1 | |
| SCHEMBL3556060 | 0.79 | ALDH1A1 (0.44) | ALDH1A1ALDH1A3SMN1; SMN2HTTMEN1 | |
| SCHEMBL23884752 | 0.77 | MAPT (0.62) | ALDH1A1ALDH1A3SMN1; SMN2HTTMEN1 | |
| SCHEMBL29990141 | 0.76 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163746-B2 | Azolecarboxamide derivative | ASTELLAS PHARMA INC. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | GPR17, NTRK1, TRPV1 | ALDH1A1 975/4885ALDH1A3 738/4885SMN1; SMN2 3601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.