Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | ATP1A1 | P05023 | 4/20 | 0.35 |
| ▸ | ATP1B1 | P05026 | 4/20 | 0.35 |
| ▸ | ATP1A3 | P13637 | 4/20 | 0.35 |
| ▸ | ATP1B2 | P14415 | 4/20 | 0.35 |
| ▸ | ATP1A2 | P50993 | 4/20 | 0.35 |
| ▸ | ATP1B3 | P54709 | 4/20 | 0.35 |
| ▸ | FXYD2 | P54710 | 4/20 | 0.35 |
| ▸ | ATP1A4 | Q13733 | 4/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | PDE9A | O76083 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 2/20 | 0.34 |
| ▸ | LDHB | P07195 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3556570 | 0.85 | LMNA (0.40) | SMN1; SMN2LMNAHSD17B10RPS6KB1ATP1A1 | |
| SCHEMBL3551237 | 0.81 | TP53 (0.38) | SMN1; SMN2TP53ATP1A1ATP1B1ATP1A3 | |
| SCHEMBL3554499 | 0.80 | IGF1R (0.39) | SMN1; SMN2RPS6KB1TP53ATP1A1ATP1B1 | |
| SCHEMBL3548594 | 0.80 | MAPK14 (0.40) | SMN1; SMN2HSD17B10RPS6KB1TP53ATP1A1 | |
| SCHEMBL3552537 | 0.80 | TP53 (0.39) | SMN1; SMN2RPS6KB1TP53ATP1A1ATP1B1 | |
| SCHEMBL3551921 | 0.80 | TP53 (0.43) | SMN1; SMN2RPS6KB1TP53ATP1A1ATP1B1 | |
| SCHEMBL3552661 | 0.80 | TP53 (0.43) | SMN1; SMN2LMNATP53HDAC8LDHA | |
| SCHEMBL3555836 | 0.79 | TP53 (0.38) | SMN1; SMN2RPS6KB1TP53ATP1A1ATP1B1 | |
| SCHEMBL3549226 | 0.79 | HDAC6 (0.39) | SMN1; SMN2RPS6KB1TP53ATP1A1ATP1B1 | |
| SCHEMBL3550460 | 0.78 | IGF1R (0.43) | SMN1; SMN2RPS6KB1TP53ATP1A1ATP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101048406-B | Novel substituted imidazole derivatives | BANYU PHARMA CO LTD | 2010-12-22 | — | — | CN | disclosed |
| US-7718801-B2 | Substituted imidazole derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-05-18 | — | — | US | disclosed |
| US-20080070894-A1 | Novel Substituted Imidazole Derivative | MSD K.K. (JP) | 2008-03-20 | — | — | US | disclosed |
| CN-101048406-A | Novel substituted imidazole derivatives | BANYU PHARMA CO LTD (JP) | 2007-10-03 | — | — | CN | disclosed |
| EP-1790650-A1 | NOVEL SUBSTITUTED IMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-05-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070894-A1 | Novel Substituted Imidazole Derivative | PLK1, CDK1, CDK11A | SMN1; SMN2 3452/4885LMNA 2017/4885HSD17B10 3515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.