Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.37 |
| ▸ | ATP1A1 | P05023 | 4/20 | 0.37 |
| ▸ | ATP1B1 | P05026 | 4/20 | 0.37 |
| ▸ | ATP1A3 | P13637 | 4/20 | 0.37 |
| ▸ | ATP1B2 | P14415 | 4/20 | 0.37 |
| ▸ | ATP1A2 | P50993 | 4/20 | 0.37 |
| ▸ | ATP1B3 | P54709 | 4/20 | 0.37 |
| ▸ | FXYD2 | P54710 | 4/20 | 0.37 |
| ▸ | ATP1A4 | Q13733 | 4/20 | 0.37 |
| ▸ | IGF1R | P08069 | 4/20 | 0.37 |
| ▸ | CDK2 | P24941 | 3/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | JUN | P05412 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3551389 | 0.85 | SMN1; SMN2 (0.38) | LMNASMN1; SMN2HSD17B10RPS6KB1ATP1A1 | |
| SCHEMBL3548956 | 0.79 | IGF1R (0.45) | RPS6KB1KITIRAK4ATP1A1ATP1B1 | |
| SCHEMBL27711831 | 0.74 | MEN1 (0.43) | LMNASMN1; SMN2HSD17B10RPS6KB1ATP1A1 | |
| SCHEMBL3556311 | 0.74 | DYRK1A (0.56) | IRAK4IGF1RCDK2DYRK1AJUN | |
| SCHEMBL1997497 | 0.70 | IRAK4 (0.50) | KITIRAK4ATP1A1ATP1B1ATP1A3 | |
| SCHEMBL1997500 | 0.70 | IRAK4 (0.50) | KITIRAK4ATP1A1ATP1B1ATP1A3 | |
| SCHEMBL3555067 | 0.68 | BRD4 (0.44) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL3555366 | 0.67 | IGF1R (0.41) | RPS6KB1ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL17933851 | 0.66 | LMNA (0.50) | LMNASMN1; SMN2HSD17B10CDK2 | |
| SCHEMBL14181331 | 0.66 | LMNA (0.50) | LMNASMN1; SMN2HSD17B10CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718801-B2 | Substituted imidazole derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-05-18 | — | — | US | disclosed |
| US-20080070894-A1 | Novel Substituted Imidazole Derivative | MSD K.K. (JP) | 2008-03-20 | — | — | US | disclosed |
| EP-1790650-A1 | NOVEL SUBSTITUTED IMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-05-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070894-A1 | Novel Substituted Imidazole Derivative | PLK1, CDK1, CDK11A | LMNA 2017/4885SMN1; SMN2 3452/4885HSD17B10 3515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.