Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.79 |
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.66 |
| ▸ | AR | P10275 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | IKBKB | O14920 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | FABP4 | P15090 | 1/20 | 0.53 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ACLY | P53396 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3558632 | 0.86 | ACLY (0.68) | MAPK1MEN1KMT2AGPR55IKBKB | |
| SCHEMBL3562211 | 0.85 | AR (0.64) | MAPK1MEN1KMT2AGPR55AR | |
| SCHEMBL3558901 | 0.85 | MAPK1 (0.57) | MAPK1MEN1KMT2AGPR55AR | |
| SCHEMBL3554085 | 0.84 | MAPK1 (0.85) | MAPK1MEN1KMT2AGPR55AR | |
| SCHEMBL3556997 | 0.81 | AR (0.61) | MAPK1MEN1KMT2AGPR55AR | |
| SCHEMBL1471566 | 0.77 | AR (0.64) | MAPK1MEN1KMT2AARHSD17B10 | |
| SCHEMBL3557116 | 0.77 | MEN1 (0.49) | MAPK1MEN1KMT2AGPR55HPGD | |
| SCHEMBL3554420 | 0.77 | ALDH1A1 (0.56) | MEN1KMT2AGPR55HSD17B10POLB | |
| SCHEMBL3563809 | 0.76 | MEN1 (0.62) | MEN1KMT2AGPR55ARPOLB | |
| SCHEMBL15480543 | 0.76 | MAPK1 (0.75) | MAPK1MEN1KMT2AHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816397-B2 | Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes | MERCK PATENT GMBH (DE) | 2010-10-19 | — | — | US | claimed |
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | MERCK PATENT GMBH (DE) | 2008-02-21 | — | — | US | claimed |
| US-7816397-B2 | Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes | MERCK PATENT GMBH (DE) | 2010-10-19 | — | — | US | disclosed |
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | MERCK PATENT GMBH (DE) | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | SLC5A1, ALDH7A1, ASS1 | MAPK1 667/4885MEN1 2548/4885KMT2A 4045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.