Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 2/20 | 0.54 |
| ▸ | UQCRB | P14927 | 1/20 | 0.54 |
| ▸ | SLC16A3 | O15427 | 10/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3558978 | 0.94 | HSD17B2 (0.57) | HSD17B2UQCRBSLC16A3CA1CA2 | |
| SCHEMBL3553682 | 0.90 | SLC16A3 (0.50) | HSD17B2UQCRBSLC16A3KDM4EALDH1A1 | |
| SCHEMBL3561433 | 0.89 | ACLY (0.56) | SLC16A3KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL3562322 | 0.88 | SLC16A3 (0.56) | SLC16A3KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL3564778 | 0.87 | SLC16A3 (0.64) | SLC16A3KDM4EALDH1A1MCL1 | |
| SCHEMBL3557805 | 0.85 | SLC16A3 (0.65) | SLC16A3KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL3556080 | 0.85 | SLC16A3 (0.56) | SLC16A3KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL3554689 | 0.85 | SLC16A3 (0.64) | SLC16A3KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL3554341 | 0.85 | CCR2 (0.59) | SLC16A3KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL3554581 | 0.84 | KDM4E (0.54) | SLC16A3KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816397-B2 | Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes | MERCK PATENT GMBH (DE) | 2010-10-19 | — | — | US | claimed |
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | MERCK PATENT GMBH (DE) | 2008-02-21 | — | — | US | claimed |
| US-7816397-B2 | Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes | MERCK PATENT GMBH (DE) | 2010-10-19 | — | — | US | disclosed |
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | MERCK PATENT GMBH (DE) | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | SLC5A1, ALDH7A1, ASS1 | HSD17B2 485/4885UQCRB 162/4885SLC16A3 425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.