Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.43 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3367014 | 0.93 | MAPT (0.47) | MAPTKMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL1225270 | 0.92 | KMT2A (0.50) | MAPTKMT2AALDH1A1RAB9AGAA | |
| SCHEMBL3365486 | 0.89 | SMN1; SMN2 (0.42) | MAPTKMT2AALDH1A1RAB9AHPGD | |
| SCHEMBL3370342 | 0.84 | KMT2A (0.45) | MAPTKMT2AALDH1A1RAB9AGAA | |
| SCHEMBL3367196 | 0.75 | SCN4A (0.54) | ALDH1A1RAB9ALMNAHTTNPC1 | |
| SCHEMBL3366888 | 0.69 | HPGD (0.47) | MAPTKMT2AALDH1A1RAB9AGAA | |
| SCHEMBL11746060 | 0.68 | MAPT (0.40) | MAPTKMT2AALDH1A1RAB9ANPSR1 | |
| SCHEMBL6340449 | 0.64 | ENPP3 (0.49) | MAPTKMT2AALDH1A1RAB9AGAA | |
| SCHEMBL10918704 | 0.64 | CTRC (0.76) | — | |
| SCHEMBL1531102 | 0.63 | FAAH (0.49) | MAPTKMT2ARAB9AGAAELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2266960-B1 | Aryl-substituted pyrazoles, imidazoles, oxazoles, thiazoles and pyrroles as anticonvulsants | EURO CELTIQUE SA (LU) | 2014-01-22 | — | — | EP | disclosed |
| EP-2266960-A2 | Aryl-substituted pyrazoles, imidazoles, oxazoles, thiazoles and pyrroles as anticonvulsants | EURO-CELTIQUE S.A. (LU) | 2010-12-29 | — | — | EP | disclosed |