Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL142183 | 0.80 | — | — | |
| SCHEMBL9375936 | 0.79 | TRPA1 (0.43) | MAPTTRPA1KCNK3KCNK9CYP3A4 | |
| SCHEMBL30466241 | 0.79 | TRPA1 (0.43) | MAPTTRPA1KCNK3KCNK9CYP3A4 | |
| Hydrochloric Acid SCHEMBL4253131 | 0.78 | — | — | |
| SCHEMBL27536645 | 0.78 | — | — | |
| SCHEMBL564791 | 0.77 | MAPT (0.44) | MAPTTRPA1KCNK3KCNK9CYP3A4 | |
| SCHEMBL8866037 | 0.77 | TRPA1 (0.48) | MAPTTRPA1KCNK3KCNK9CYP3A4 | |
| Formaldehyde SCHEMBL27533174 | 0.76 | MAPT (0.47) | MAPTTRPA1KCNK3KCNK9CYP3A4 | |
| SCHEMBL11527326 | 0.76 | MAPT (0.46) | MAPTTRPA1KCNK3KCNK9CYP3A4 | |
| Hydrochloric Acid SCHEMBL9261456 | 0.76 | MAPT (0.43) | MAPTTRPA1KCNK3KCNK9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-101203518-B | Fluorene derivative, composition containing the same and use thereof | AVENTIS PHARMA SA | 2013-07-24 | — | — | CN | disclosed |
| US-7674795-B2 | Fluorene derivatives, composition containing said derivatives and the use thereof | AVENTIS PHARMA SA (FR) | 2010-03-09 | — | — | US | disclosed |
| US-7517881-B2 | Triazine derivatives, their preparation and therapeutic application thereof | AVENTIS PHARMA S.A. (FR) | 2009-04-14 | — | — | US | disclosed |
| US-7442485-B2 | Lithographic process involving on press development | FUJIFILM CORPORATION (JP) | 2008-10-28 | — | — | US | disclosed |
| US-20080153837-A1 | Novel Fluorene Derivatives, Composition Containing Said Derivatives and the Use Thereof | AVENTIS PHARMA S.A. (FR) | 2008-06-26 | — | — | US | disclosed |
| CN-101203518-A | Novel fluorene derivatives, compositions containing same and uses thereof | AVENTIS PHARMA SA (FR) | 2008-06-18 | — | — | CN | disclosed |
| US-20080096891-A1 | TRIAZINE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC APPLICATION THEREOF | AVENTIS PHARMA S.A. (FR) | 2008-04-24 | — | — | US | disclosed |
| US-RE39820-E1 | As anticholinergics, administered by inhalation, they are useful for the treatment of chronic obstructive bronchitis or slight to moderately severe asthma; administered by the intravenous or oral routes, they are useful for the treatment of vagally induced sinus bradycardia | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2007-09-04 | — | — | US | disclosed |
| EP-1484177-B1 | Lithographic process involving on press development | FUJIFILM CORP (JP) | 2007-08-29 | — | — | EP | disclosed |
| US-5654314-A | RESPIRATORY SYSTEM DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 1997-08-05 | — | — | US | disclosed |
| US-5610163-A | ANTICHOLINERGIC AGENTS | BOEHRINGER INGELHEIM GMBH (DE) | 1997-03-11 | — | — | US | disclosed |
| EP-0418716-B1 | Thienylcarboxylic acid ester of aminoalcohols, their quaternary products, their preparation and use of the compounds | BOEHRINGER INGELHEIM KG (DE) | 1994-04-06 | — | — | EP | disclosed |
| EP-0579615-A1 | NEW BI- AND TRICYCLIC AMINOALCOHOL ESTERS, THEIR PREPARATION AND THEIR USE IN MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GmbH (DE) | 1994-01-26 | — | — | EP | disclosed |
| WO-1992016528-A1 | NEW BI- AND TRICYCLIC AMINOALCOHOL ESTERS, THEIR PREPARATION AND THEIR USE IN MEDICAMENTS | BOEHRINGER INGELHEIM KG (DE) | 1992-10-01 | — | — | WO | disclosed |
| WO-1991004252-A1 | NEW ESTERS OF THIENYL CARBOXYLIC ACIDS AND AMINO ALCOHOLS, THEIR QUATERNIZATION PRODUCTS, AND MANUFACTURE AND USE OF SAID COMPOUNDS | BOEHRINGER INGELHEIM KG (DE) | 1991-04-04 | — | — | WO | disclosed |
| EP-0418716-A1 | Thienylcarboxylic acid ester of aminoalcohols, their quaternary products, their preparation and use of the compounds | BOEHRINGER INGELHEIM KG (DE) | 1991-03-27 | — | — | EP | disclosed |
| US-4871864-A | Carbamoyloxythiophene fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1989-10-03 | — | — | US | disclosed |
| US-4839381-A | FUNGICIDES, PESTICIDES; RICE PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-13 | — | — | US | disclosed |
| US-4757085-A | Pharmaceuticals | BAYER AKTIENGESELLSCHAFT (DE) | 1988-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096891-A1 | TRIAZINE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC APPLICATION THEREOF | CYP11B2, IL5, TBXA2R | MAPT 3027/4885CPT1B 1354/4885TRPA1 3324/4885 |
| US-20080153837-A1 | Novel Fluorene Derivatives, Composition Containing Said Derivatives and the Use Thereof | HSP90B1, HSP90AB1, HSP90AA1 | MAPT 844/4885CPT1B 3356/4885TRPA1 2234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.