Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.49 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.49 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.48 |
| ▸ | LCK | P06239 | 4/20 | 0.48 |
| ▸ | FLT3 | P36888 | 2/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | LYN | P07948 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | AKT2 | P31751 | 1/20 | 0.45 |
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
| ▸ | FRK | P42685 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3556311 | 0.87 | DYRK1A (0.56) | MAPK14MAPK13MAPK12MAPK11LCK | |
| SCHEMBL3551857 | 0.86 | MAPK13 (0.49) | MAPK14MAPK13MAPK12MAPK11CAMK2D | |
| SCHEMBL3555366 | 0.81 | IGF1R (0.41) | MAPK14MAPK13MAPK12MAPK11LCK | |
| SCHEMBL3555802 | 0.80 | FLT3 (0.54) | MAPK14MAPK13MAPK12MAPK11LCK | |
| SCHEMBL3548953 | 0.80 | FLT3 (0.49) | MAPK14MAPK13MAPK12MAPK11CAMK2D | |
| SCHEMBL14561207 | 0.77 | MAPK14 (0.69) | MAPK14MAPK13LCKFLT3PRKD3 | |
| SCHEMBL3555283 | 0.74 | FLT3 (0.47) | MAPK14MAPK13MAPK12MAPK11LCK | |
| SCHEMBL3548797 | 0.73 | CDK2 (0.68) | MAPK14MAPK13MAPK12MAPK11LCK | |
| SCHEMBL3557012 | 0.72 | CAMK2D (0.47) | MAPK14MAPK13MAPK12MAPK11CAMK2D | |
| SCHEMBL3553849 | 0.70 | MAPK14 (0.48) | MAPK14MAPK13MAPK12MAPK11LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718801-B2 | Substituted imidazole derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-05-18 | — | — | US | disclosed |
| US-20080070894-A1 | Novel Substituted Imidazole Derivative | MSD K.K. (JP) | 2008-03-20 | — | — | US | disclosed |
| EP-1790650-A1 | NOVEL SUBSTITUTED IMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-05-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070894-A1 | Novel Substituted Imidazole Derivative | PLK1, CDK1, CDK11A | MAPK14 680/4885MAPK13 678/4885MAPK12 957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.