Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | FABP4 | P15090 | 1/20 | 0.48 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | IDH1 | O75874 | 3/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3558029 | 0.89 | ALPL (0.50) | FABP4FABP5ALPLIDH1SLC22A12 | |
| SCHEMBL3553044 | 0.88 | ALDH1A1 (0.62) | ALDH1A1KMT2APTK2BMMP2MMP13 | |
| SCHEMBL3556754 | 0.88 | ALDH1A1 (0.57) | ALDH1A1SLC22A12KMT2APTK2BMMP2 | |
| SCHEMBL3557987 | 0.88 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1FFAR4 | |
| SCHEMBL3557863 | 0.86 | ALDH1A1 (0.56) | ALDH1A1FABP4FABP5KMT2APTK2B | |
| SCHEMBL3556589 | 0.86 | ALPL (0.47) | ALDH1A1FABP4FABP5ALPLIDH1 | |
| SCHEMBL3556010 | 0.84 | FFAR4 (0.47) | FABP4FABP5ALPLIDH1SLC22A12 | |
| SCHEMBL3558986 | 0.82 | ALDH1A1 (0.63) | ALDH1A1KMT2APTK2BMEN1 | |
| SCHEMBL3559363 | 0.82 | POLB (0.52) | ALDH1A1FABP4FABP5IDH1KMT2A | |
| SCHEMBL3558810 | 0.81 | MRGPRX1 (0.51) | ALDH1A1ALPLSLC22A12KMT2APTK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816397-B2 | Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes | MERCK PATENT GMBH (DE) | 2010-10-19 | — | — | US | claimed |
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | MERCK PATENT GMBH (DE) | 2008-02-21 | — | — | US | claimed |
| US-7816397-B2 | Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes | MERCK PATENT GMBH (DE) | 2010-10-19 | — | — | US | disclosed |
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | MERCK PATENT GMBH (DE) | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | SLC5A1, ALDH7A1, ASS1 | ALDH1A1 61/4885FABP4 251/4885FABP5 799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.