Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NNMT | P40261 | 1/20 | 0.31 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2262918 | 1.00 | USP2 (0.39) | USP2NPSR1HDAC3HDAC4HDAC1 | |
| Trifluoroacetic Acid SCHEMBL2262922 | 0.96 | USP2 (0.37) | USP2NPSR1HDAC3HDAC4HDAC1 | |
| Trifluoroacetic Acid SCHEMBL6756338 | 0.86 | CES1 (0.34) | USP2KMT2ACES1NNMT | |
| Bicarbonate SCHEMBL28802052 | 0.83 | USP2 (0.46) | USP2KMT2ANNMT | |
| Trifluoroacetic Acid SCHEMBL2160769 | 0.81 | CES1 (0.34) | NPSR1HDAC3HDAC4HDAC1HDAC7 | |
| Acetic Acid SCHEMBL2039260 | 0.80 | USP2 (0.45) | USP2KMT2ANNMT | |
| Acetic Acid SCHEMBL7068267 | 0.80 | USP2 (0.45) | USP2KMT2ANNMT | |
| Oxalic Acid SCHEMBL21814394 | 0.80 | USP2 (0.45) | USP2KMT2ANNMT | |
| Acetic Acid SCHEMBL9159557 | 0.78 | USP2 (0.43) | USP2KMT2ANNMT | |
| Acetic Acid SCHEMBL2048768 | 0.78 | USP2 (0.43) | USP2KMT2ANNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007510649-A | — | — | 2007-04-26 | — | — | JP | claimed |
| EP-1682550-A4 | SUBSTITUTED NAPHTHYRIDINONE DERIVATIVES | MERCK & CO INC (US) | 2007-01-03 | — | — | EP | claimed |
| EP-1682550-A1 | SUBSTITUTED NAPHTHYRIDINONE DERIVATIVES | Merck & Co., Inc. (US) | 2006-07-26 | — | — | EP | claimed |
| CN-1628087-A | Production of alkenones | SOLVAY FLUOR & DERIVATE (DE) | 2005-06-15 | — | — | CN | claimed |
| WO-2005047285-A1 | SUBSTITUTED NAPHTHYRIDINONE DERIVATIVES | MERCK & CO., INC. (US) | 2005-05-26 | — | — | WO | claimed |
| CN-114956969-B | Preparation method of 4-ethoxy-1, 1-trifluoro-3-butene-2-ketone | 永农生物科学有限公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-110573137-B | Odorless thiols for permanent wave, straightening and dehairing applications | 宝洁公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-114956969-A | Preparation method of 4-ethoxy-1, 1, 1-trifluoro-3-butene-2-one | 永农生物科学有限公司 | 2022-08-30 | — | — | CN | disclosed |
| EP-3614999-B1 | ODORLESS THIOLS FOR PERMANENT WAVING, STRAIGHTENING AND DEPILATORY APPLICATIONS | PROCTER & GAMBLE (US) | 2022-07-13 | — | — | EP | disclosed |
| CN-110573137-A | Odorless thiols for long lasting wave, straightening and depilatory applications | 宝洁公司 | 2019-12-13 | — | — | CN | disclosed |
| US-7834015-B2 | treatment of cancer, inflammatory diseases, reperfusion injuries, ischaemic conditions, stroke, renal failure, cardiovascular diseases, neurodegenerative diseases, retroviral infections, retinal damage, skin senescence and UV skin damage, and as chemosensitizers or radiosensitizers for cancer treatment | INSTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2010-11-16 | — | — | US | disclosed |
| US-20090209523-A1 | Pyrrolo[1,2-A] Pyrazin-1(2H)-One and Pyrrolo[1,2-D][1,2,4]Triazin-1(2H)-One Derivatives as Inhibitors of Poly(Adp-Ribose)Polymerase (Parp) | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2009-08-20 | — | — | US | disclosed |
| CN-1628087-A | Production of alkenones | SOLVAY FLUOR & DERIVATE (DE) | 2005-06-15 | — | — | CN | disclosed |
| US-6759420-B1 | LOW MOLECULAR WEIGHT, FACTOR XA SPECIFIC BLOOD CLOTTING INHIBITORS WITHOUT SIDE EFFECTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-07-06 | — | — | US | disclosed |
| EP-0871628-A1 | QUINOLIZINONE TYPE COMPOUNDS | Abbott Laboratories (US) | 1998-10-21 | — | — | EP | disclosed |
| US-5726182-A | TREATMENT OF BACTERIAL INFECTIONS | ABBOTT LABORATORIES (US) | 1998-03-10 | — | — | US | disclosed |
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | disclosed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209523-A1 | Pyrrolo[1,2-A] Pyrazin-1(2H)-One and Pyrrolo[1,2-D][1,2,4]Triazin-1(2H)-One Derivatives as Inhibitors of Poly(Adp-Ribose)Polymerase (Parp) | PARP1, PARP2, PARP11 | USP2 3125/4885NPSR1 3785/4885HDAC3 2144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.