Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | NNMT | P40261 | 1/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | CHAT | P28329 | 2/20 | 0.31 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL2039260 | 1.00 | USP2 (0.45) | USP2CA1NNMTSLC22A2SLC22A1 | |
| Acetic Acid SCHEMBL2048768 | 0.97 | USP2 (0.43) | USP2CA1NNMTSLC22A2SLC22A1 | |
| Acetic Acid SCHEMBL9159557 | 0.97 | USP2 (0.43) | USP2CA1NNMTSLC22A2SLC22A1 | |
| Bicarbonate SCHEMBL28802052 | 0.92 | USP2 (0.46) | USP2CA1NNMTSLC22A2SLC22A1 | |
| Oxalic Acid SCHEMBL21814394 | 0.89 | USP2 (0.45) | USP2CA1NNMTSLC22A2SLC22A1 | |
| Oxalic Acid SCHEMBL21814395 | 0.82 | NNMT (0.38) | USP2NNMTSLC22A2SLC22A1SLC22A3 | |
| Fumaric Acid SCHEMBL9625739 | 0.82 | USP2 (0.41) | USP2NNMTSLC22A2SLC22A1SLC22A3 | |
| Succinic Acid SCHEMBL2048766 | 0.82 | USP2 (0.41) | USP2CA1NNMTAPOBEC3AAPOBEC3G | |
| Dimethylcarbate SCHEMBL21483331 | 0.82 | USP2 (0.41) | USP2NNMTSLC22A2SLC22A1SLC22A3 | |
| SCHEMBL10408710 | 0.82 | USP2 (0.41) | USP2NNMTSLC22A2SLC22A1SLC22A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0458502-B1 | Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom | DOW GLOBAL TECHNOLOGIES INC (US) | 2003-06-18 | — | — | EP | claimed |
| US-5169473-A | Complex of an onium, arsenic or amine compound and boric acid; advanced polyepoxides; storage stability | THE DOW CHEMICAL COMPANY (US) | 1992-12-08 | — | — | US | claimed |
| EP-0458502-A2 | Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom | THE DOW CHEMICAL COMPANY (US) | 1991-11-27 | — | — | EP | claimed |
| EP-0458502-B1 | Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom | DOW GLOBAL TECHNOLOGIES INC (US) | 2003-06-18 | — | — | EP | disclosed |
| EP-0328020-B1 | Use of a catalyst in epoxy compositions | DOW CHEMICAL CO (US) | 1996-10-09 | — | — | EP | disclosed |
| EP-0639599-A1 | Solvent system and epoxy resin composition | THE DOW CHEMICAL COMPANY (US) | 1995-02-22 | — | — | EP | disclosed |
| US-5342865-A | Solvent system | THE DOW CHEMICAL COMPANY (US) | 1994-08-30 | — | — | US | disclosed |
| EP-0567248-A1 | Solvent system | THE DOW CHEMICAL COMPANY (US) | 1993-10-27 | — | — | EP | disclosed |
| EP-0553887-A2 | Catalysts and epoxy resin composition containing the same | THE DOW CHEMICAL COMPANY (US) | 1993-08-04 | — | — | EP | disclosed |
| US-5169473-A | Complex of an onium, arsenic or amine compound and boric acid; advanced polyepoxides; storage stability | THE DOW CHEMICAL COMPANY (US) | 1992-12-08 | — | — | US | disclosed |
| EP-0458502-A2 | Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom | THE DOW CHEMICAL COMPANY (US) | 1991-11-27 | — | — | EP | disclosed |
| US-4925901-A | STORAGE STAABILITY, ONIUM ION CATALYST | THE DOW CHEMICAL COMPANY (US) | 1990-05-15 | — | — | US | disclosed |
| EP-0328020-A2 | Use of a catalyst in epoxy compositions | THE DOW CHEMICAL COMPANY (US) | 1989-08-16 | — | — | EP | disclosed |