Acetic Acid

Acetic Acid

SCHEMBL2039260

CC(=O)[O-].C[n+]1ccccc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.45
CA1 P00915 2/20 0.44
NNMT P40261 1/20 0.35
SLC22A2 O15244 1/20 0.35
SLC22A1 O15245 1/20 0.35
SLC22A3 O75751 1/20 0.35
SLC6A4 P31645 1/20 0.35
CA4 P22748 2/20 0.33
APOBEC3A P31941 2/20 0.32
APOBEC3G Q9HC16 2/20 0.32
CTDSP1 Q9GZU7 1/20 0.32
KMT2A Q03164 1/20 0.32
FFAR3 O14843 1/20 0.32
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32
CHAT P28329 2/20 0.31
BCHE P06276 2/20 0.31
LMNA P02545 1/20 0.31
GLA P06280 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL7068267 1.00 USP2 (0.45) USP2CA1NNMTSLC22A2SLC22A1
Acetic Acid SCHEMBL2048768 0.97 USP2 (0.43) USP2CA1NNMTSLC22A2SLC22A1
Acetic Acid SCHEMBL9159557 0.97 USP2 (0.43) USP2CA1NNMTSLC22A2SLC22A1
Bicarbonate SCHEMBL28802052 0.92 USP2 (0.46) USP2CA1NNMTSLC22A2SLC22A1
Oxalic Acid SCHEMBL21814394 0.89 USP2 (0.45) USP2CA1NNMTSLC22A2SLC22A1
Oxalic Acid SCHEMBL21814395 0.82 NNMT (0.38) USP2NNMTSLC22A2SLC22A1SLC22A3
Fumaric Acid SCHEMBL9625739 0.82 USP2 (0.41) USP2NNMTSLC22A2SLC22A1SLC22A3
Succinic Acid SCHEMBL2048766 0.82 USP2 (0.41) USP2CA1NNMTAPOBEC3AAPOBEC3G
Dimethylcarbate SCHEMBL21483331 0.82 USP2 (0.41) USP2NNMTSLC22A2SLC22A1SLC22A3
SCHEMBL10408710 0.82 USP2 (0.41) USP2NNMTSLC22A2SLC22A1SLC22A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2638123-B1 WORKING MEDIUM FOR ABSORPTION HEAT PUMPS EVONIK DEGUSSA GMBH (DE) 2016-08-31 EP claimed
EP-2638123-A1 WORKING MEDIUM FOR ABSORPTION HEAT PUMPS Evonik Degussa GmbH (DE) 2013-09-18 EP claimed
US-20130219949-A1 WORKING MEDIUM FOR ABSORPTION HEAT PUMPS EVONIK DEGUSSA GMBH (DE) 2013-08-29 US claimed
WO-2012062656-A1 WORKING MEDIUM FOR ABSORPTION HEAT PUMPS EVONIK DEGUSSA GMBH (DE) 2012-05-18 WO claimed
EP-0458502-B1 Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom DOW GLOBAL TECHNOLOGIES INC (US) 2003-06-18 EP claimed
US-5169473-A Complex of an onium, arsenic or amine compound and boric acid; advanced polyepoxides; storage stability THE DOW CHEMICAL COMPANY (US) 1992-12-08 US claimed
EP-0458502-A2 Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom THE DOW CHEMICAL COMPANY (US) 1991-11-27 EP claimed
US-20240393290-A1 ELECTROCHEMICAL GAS SENSOR AND ELECTROLYTE FOR AN ELECTROCHEMICAL GAS SENSOR Dräger Safety AG & Co. KGaA (DE) 2024-11-28 US disclosed
CN-117999475-A Electrochemical gas sensor and electrolyte for electrochemical gas sensor 德尔格安全股份两合公司 2024-05-07 CN disclosed
EP-4196779-A1 ELECTROCHEMICAL GAS SENSOR AND ELECTROLYTE FOR AN ELECTROCHEMICAL GAS SENSOR Dräger Safety AG & Co. KGaA (DE) 2023-06-21 EP disclosed
WO-2023046704-A1 ELECTROCHEMICAL GAS SENSOR AND ELECTROLYTE FOR AN ELECTROCHEMICAL GAS SENSOR Dräger Safety AG & Co. KGaA (DE) 2023-03-30 WO disclosed
EP-4155723-A1 ELECTROCHEMICAL GAS SENSOR AND ELECTROLYTE FOR AN ELECTROCHEMICAL GAS SENSOR Dräger Safety AG & Co. KGaA (DE) 2023-03-29 EP disclosed
CN-113366156-A Composition and method for fabricating nickel interconnects 麦克德米德乐思公司 2021-09-07 CN disclosed
EP-0553887-A2 Catalysts and epoxy resin composition containing the same THE DOW CHEMICAL COMPANY (US) 1993-08-04 EP disclosed
US-5169473-A Complex of an onium, arsenic or amine compound and boric acid; advanced polyepoxides; storage stability THE DOW CHEMICAL COMPANY (US) 1992-12-08 US disclosed
EP-0458502-A2 Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom THE DOW CHEMICAL COMPANY (US) 1991-11-27 EP disclosed
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US disclosed
US-4892944-A Process for producing quaternary salts MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1990-01-09 US disclosed
EP-0328020-A2 Use of a catalyst in epoxy compositions THE DOW CHEMICAL COMPANY (US) 1989-08-16 EP disclosed
US-4200720-A HYDROXIDE OR NUCLEOPHILIC SALT OF A MONOVALENT CATION THE DOW CHEMICAL COMPANY (US) 1980-04-29 US disclosed