Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | NNMT | P40261 | 1/20 | 0.34 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CHAT | P28329 | 1/20 | 0.30 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7068267 | 0.97 | USP2 (0.45) | USP2CA1NNMTSLC22A2SLC22A1 | |
| Acetic Acid SCHEMBL2039260 | 0.97 | USP2 (0.45) | USP2CA1NNMTSLC22A2SLC22A1 | |
| Acetic Acid SCHEMBL2048768 | 0.95 | USP2 (0.43) | USP2CA1NNMTSLC22A2SLC22A1 | |
| Bicarbonate SCHEMBL28802052 | 0.89 | USP2 (0.46) | USP2CA1NNMTSLC22A2SLC22A1 | |
| Oxalic Acid SCHEMBL21814394 | 0.86 | USP2 (0.45) | USP2CA1NNMTSLC22A2SLC22A1 | |
| Oxalic Acid SCHEMBL21814395 | 0.80 | NNMT (0.38) | USP2NNMTSLC22A2SLC22A1SLC22A3 | |
| Succinic Acid SCHEMBL2048766 | 0.80 | USP2 (0.41) | USP2CA1NNMTAPOBEC3AAPOBEC3G | |
| Fumaric Acid SCHEMBL9625739 | 0.80 | USP2 (0.41) | USP2NNMTSLC22A2SLC22A1SLC22A3 | |
| Propionic Acid SCHEMBL2456076 | 0.80 | USP2 (0.41) | USP2CA1NNMTSLC22A2SLC22A1 | |
| SCHEMBL10408710 | 0.80 | USP2 (0.41) | USP2NNMTSLC22A2SLC22A1SLC22A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5438140-A | Using cyclic ammonium compounds as brighteners | BASF AKTIENGESELLSCHAFT (DE) | 1995-08-01 | — | — | US | disclosed |