Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.63 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.55 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CCR1 | P32246 | 2/20 | 0.52 |
| ▸ | CCR2 | P41597 | 2/20 | 0.52 |
| ▸ | GPR27 | Q9NS67 | 5/20 | 0.50 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.50 |
| ▸ | ACLY | P53396 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3562492 | 0.91 | PSEN1 (0.57) | ARCACNA1BCACNA1HALDH1A1CCR1 | |
| SCHEMBL3552950 | 0.90 | PTPN5 (0.54) | ARCACNA1BALDH1A1MEN1KMT2A | |
| SCHEMBL3557987 | 0.90 | ALDH1A1 (0.53) | ARCACNA1BALDH1A1GPR27AVPR2 | |
| SCHEMBL3559135 | 0.89 | AR (0.62) | ARCACNA1BCACNA1HALDH1A1CCR2 | |
| SCHEMBL3558986 | 0.89 | ALDH1A1 (0.63) | ARCACNA1BALDH1A1MEN1KMT2A | |
| SCHEMBL3564010 | 0.87 | ALDH1A1 (0.58) | ARCACNA1BALDH1A1MEN1KMT2A | |
| SCHEMBL3563348 | 0.87 | ALDH1A1 (0.58) | ARCACNA1BALDH1A1MEN1KMT2A | |
| SCHEMBL3560145 | 0.87 | MEN1 (0.51) | ARCACNA1BALDH1A1MEN1KMT2A | |
| SCHEMBL3559276 | 0.86 | AR (0.61) | ARCACNA1BALDH1A1MEN1KMT2A | |
| SCHEMBL3561723 | 0.86 | PGR (0.57) | CACNA1BALDH1A1GPR27AVPR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816397-B2 | Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes | MERCK PATENT GMBH (DE) | 2010-10-19 | — | — | US | claimed |
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | MERCK PATENT GMBH (DE) | 2008-02-21 | — | — | US | claimed |
| US-7816397-B2 | Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes | MERCK PATENT GMBH (DE) | 2010-10-19 | — | — | US | disclosed |
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | MERCK PATENT GMBH (DE) | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | SLC5A1, ALDH7A1, ASS1 | AR 3412/4885CACNA1B 1921/4885CACNA1H 2058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.