SCHEMBL3555823

SCHEMBL3555823

CCC(OC(C)=O)C(C)C1OC1CC(C)/C=C/C=C(\C)C1OC(=O)CC(O)CCC(C)(O)C(OC(C)=O)/C=C/C1C

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SF3B3 Q15393 10/20 0.65
HMGCR P04035 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1505127 0.95 SF3B3 (0.63) SF3B3
SCHEMBL13714959 0.95 SF3B3 (0.61) SF3B3
SCHEMBL12833387 0.95 SF3B3 (0.62) SF3B3
SCHEMBL1505007 0.95 SF3B3 (0.67) SF3B3HMGCR
SCHEMBL13714902 0.95 SF3B3 (0.60) SF3B3
SCHEMBL1505037 0.94 SF3B3 (0.57) SF3B3
SCHEMBL1505113 0.94 SF3B3 (0.61) SF3B3
SCHEMBL12833616 0.93 SF3B3 (0.60) SF3B3
SCHEMBL1505029 0.93 SF3B3 (0.60) SF3B3
SCHEMBL12877318 0.93 SF3B3 (0.76) SF3B3HMGCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7026352-B1 Physiologically active substances MERCIAN CORPORATION (JP) 2006-04-11 US claimed
US-7667052-B2 Bioactive substance EISAI R&D MANAGEMENT CO., LTD. (JP) 2010-02-23 US disclosed
US-7667052-B2 Bioactive substance EISAI R&D MANAGEMENT CO., LTD. (JP) 2010-02-23 US disclosed
US-7667052-B2 Bioactive substance EISAI R&D MANAGEMENT CO., LTD. (JP) 2010-02-23 US disclosed
US-20060079572-A1 Novel bioactive substance MICROBIOPHARM JAPAN CO., LTD. (JP) 2006-04-13 US disclosed
US-7026352-B1 Physiologically active substances MERCIAN CORPORATION (JP) 2006-04-11 US disclosed
EP-1380579-A1 NOVEL PHYSIOLOGICALLY ACTIVE SUBSTANCES MERCIAN CORPORATION (JP) 2004-01-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060079572-A1 Novel bioactive substance CASP7, MMP7, BMP4 SF3B3 2363/4885HMGCR 3872/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.