Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.96 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.96 |
| ▸ | MEN1 | O00255 | 4/20 | 0.96 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.96 |
| ▸ | RYR2 | Q92736 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL88911 | 1.00 | GAA (0.96) | GAAALDH1A1MEN1KMT2ARYR2 | |
| SCHEMBL29364653 | 1.00 | GAA (0.96) | GAAALDH1A1MEN1KMT2ARYR2 | |
| Oxalic Acid SCHEMBL27314622 | 0.89 | ALDH1A1 (0.76) | GAAALDH1A1MEN1KMT2ARYR2 | |
| SCHEMBL1395667 | 0.87 | ALDH1A1 (0.74) | GAAALDH1A1MEN1KMT2ARYR2 | |
| Bromide SCHEMBL9143254 | 0.85 | ALDH1A1 (0.71) | GAAALDH1A1MEN1KMT2ARYR2 | |
| SCHEMBL4488535 | 0.85 | ALDH1A1 (0.71) | GAAALDH1A1MEN1KMT2ARYR2 | |
| SCHEMBL13646789 | 0.81 | GAA (0.65) | GAAALDH1A1MEN1KMT2ARYR2 | |
| SCHEMBL1367372 | 0.75 | MEN1 (0.58) | GAAALDH1A1MEN1KMT2ARYR2 | |
| Bromide SCHEMBL11683988 | 0.74 | ALDH1A1 (0.57) | GAAALDH1A1MEN1KMT2ARYR2 | |
| Hydrochloric Acid SCHEMBL29051623 | 0.74 | ALDH1A1 (0.63) | GAAALDH1A1MEN1KMT2ARYR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687495-B2 | Substituted piperidines | SPEEDEL EXPERIMENTA AG (CH) | 2010-03-30 | — | — | US | disclosed |
| US-20080171748-A1 | Substituted piperidines | NOVARTIS AG (CH) | 2008-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171748-A1 | Substituted piperidines | REN, ACE, AGTR2 | GAA 208/4885ALDH1A1 222/4885MEN1 2843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.