⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2712850 | 0.98 | TAAR1 (0.43) | — | |
| SCHEMBL94688 | 0.80 | — | — | |
| SCHEMBL12311962 | 0.80 | — | — | |
| SCHEMBL9879846 | 0.79 | TAAR1 (0.44) | — | |
| SCHEMBL24925777 | 0.78 | — | — | |
| SCHEMBL12891886 | 0.78 | — | — | |
| SCHEMBL8801431 | 0.78 | — | — | |
| SCHEMBL19274402 | 0.78 | ALOX5 (0.41) | — | |
| SCHEMBL13440137 | 0.78 | — | — | |
| SCHEMBL28357794 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790900-B2 | Method for producing an optically active nitro compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-09-07 | — | — | US | claimed |
| CN-110724147-A | Ticagrelor derivative and preparation method and application thereof | 浙江乐普药业股份有限公司 | 2020-01-24 | — | — | CN | disclosed |
| US-20140329746-A1 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2014-11-06 | — | — | US | disclosed |
| US-8835654-B2 | Method and compositions for treating amyloid-related diseases | BHI LIMITED PARTNERSHIP (CA) | 2014-09-16 | — | — | US | disclosed |
| US-20120015911-A1 | METHOD AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | BELLUS HEALTH INC. (CA) | 2012-01-19 | — | — | US | disclosed |
| US-8044100-B2 | Methods and compositions for treating amyloid-related diseases | BELLUS HEALTH INC. (CA) | 2011-10-25 | — | — | US | disclosed |
| EP-2055689-B1 | Method for producing an optically active nitro compound | SUMITOMO CHEMICAL CO (JP) | 2011-06-29 | — | — | EP | disclosed |
| US-7790900-B2 | Method for producing an optically active nitro compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-09-07 | — | — | US | disclosed |
| WO-2009095253-A1 | 6-HALO-PYRAZOLO[1, 5-A]PYRIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR (MGLUR) MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2009-08-06 | — | — | WO | disclosed |
| EP-2054421-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | Merz Pharma GmbH & Co. KGaA (DE) | 2009-05-06 | — | — | EP | disclosed |
| EP-0550631-B1 | COMPOUNDS HAVING ANTIHYPERTENSIVE AND ANTI-ISCHEMIC PROPERTIES | RHONE POULENC RORER INT (US) | 1997-01-02 | — | — | EP | disclosed |
| US-5561134-A | ADENOSINE DERIVATIVES | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-10-01 | — | — | US | disclosed |
| WO-1995028160-A1 | COMPOUNDS HAVING ANTIHYPERTENSIVE, CARDIOPROTECTIVE, ANTI-ISCHEMIC AND ANTILIPOLYTIC PROPERTIES | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1995-10-26 | — | — | WO | disclosed |
| US-5364862-A | Adenosine derivatives | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1994-11-15 | — | — | US | disclosed |
| EP-0550631-A4 | COMPOUNDS HAVING ANTIHYPERTENSIVE AND ANTI-ISCHEMIC PROPERTIES | RHONE POULENC RORER INT (US) | 1994-08-10 | — | — | EP | disclosed |
| EP-0550631-A1 | COMPOUNDS HAVING ANTIHYPERTENSIVE AND ANTI-ISCHEMIC PROPERTIES. | RHONE POULENC RORER INT (US) | 1993-07-14 | — | — | EP | disclosed |
| EP-0522956-A2 | Preparation of 2-(2-thienyl) ethylamine and synthesis of thieno [3,2-C] pyridine derivatives therefrom | SANOFI (FR) | 1993-01-13 | — | — | EP | disclosed |
| WO-1992005177-A1 | COMPOUNDS HAVING ANTIHYPERTENSIVE AND ANTI-ISCHEMIC PROPERTIES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-04-02 | — | — | WO | disclosed |
| US-4242474-A | A POLYHYDROXY ACRYLIC ESTER REACTED WITH AN ISOCYANATE TERMINATED POLYOXYALKYLENE GLYCOL; BIOPOLYMERS | TERUMO CORPORATION (JP) | 1980-12-30 | — | — | US | disclosed |
| US-4128561-A | Process for the preparation of 2-(2-thienyl)-ethylamine and derivatives thereof | PARCOR (FR) | 1978-12-05 | — | — | US | disclosed |