⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24925777 | 1.00 | — | — | |
| SCHEMBL12891886 | 1.00 | — | — | |
| SCHEMBL5481200 | 0.83 | ALOX5 (0.42) | — | |
| SCHEMBL94688 | 0.80 | — | — | |
| SCHEMBL12311962 | 0.80 | — | — | |
| SCHEMBL29181679 | 0.79 | ALOX5 (0.42) | — | |
| SCHEMBL27987923 | 0.79 | RAB9A (0.50) | — | |
| SCHEMBL13440137 | 0.78 | — | — | |
| SCHEMBL355658 | 0.78 | — | — | |
| SCHEMBL19274402 | 0.78 | ALOX5 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522956-B1 | Preparation of 2-(2-thienyl) ethylamine and synthesis of thieno [3,2-C] pyridine derivatives therefrom | SANOFI SA (FR) | 1997-02-05 | — | — | EP | disclosed |
| EP-0522956-A2 | Preparation of 2-(2-thienyl) ethylamine and synthesis of thieno [3,2-C] pyridine derivatives therefrom | SANOFI (FR) | 1993-01-13 | — | — | EP | disclosed |