Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL604916 | 0.89 | TAAR1 (0.58) | TAAR1HTR2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17092626 | 0.84 | HRH1 (0.46) | TAAR1ALOX5CES2CES1KEAP1 | |
| SCHEMBL5796511 | 0.81 | — | — | |
| SCHEMBL325230 | 0.81 | HRH1 (0.50) | TAAR1HTR2AALOX5SLC6A2SLC6A4 | |
| SCHEMBL355658 | 0.79 | — | — | |
| SCHEMBL5930876 | 0.79 | — | — | |
| SCHEMBL4131049 | 0.79 | — | — | |
| SCHEMBL17959499 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL28689785 | 0.79 | TAAR1 (0.39) | TAAR1ALOX5CES2CES1KEAP1 | |
| SCHEMBL10862055 | 0.78 | CES2 (0.38) | ALOX5CES2CES1KEAP1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274324-B1 | PROCESS FOR THE PREPARATION OF THIENYLETHYL AMINES, AND DITHIENYLETHYL AMINES SO OBTAINED | SANOFI (FR) | 1991-02-06 | — | — | EP | disclosed |
| EP-0274324-A1 | Process for the preparation of thienylethyl amines, and dithienylethyl amines so obtained | SANOFI (FR) | 1988-07-13 | — | — | EP | disclosed |
| WO-1988003148-A2 | HETEROAROMATIC DERIVATIVES OF ADENOSIDE | WARNER-LAMBERT COMPANY (US) | 1988-05-05 | — | — | WO | disclosed |