Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20624642 | 0.82 | CYP3A4 (0.41) | MAPTKMT2AL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL5190617 | 0.82 | POLB (0.56) | MAPTRAB9AKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL9822717 | 0.79 | ALDH1A1 (0.58) | MAPTALDH1A1HTTKDM4EHPGD | |
| SCHEMBL11329697 | 0.76 | ALDH1A1 (0.48) | MAPTRAB9AKMT2AAPAF1ALDH1A1 | |
| SCHEMBL10569660 | 0.75 | HPGD (0.66) | MAPTRAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL2805600 | 0.71 | POLB (0.57) | MAPTRAB9AKMT2AL3MBTL1APAF1 | |
| SCHEMBL2590278 | 0.71 | PTGS1 (0.50) | MAPTKMT2AL3MBTL1KDM4ENQO1 | |
| SCHEMBL546834 | 0.71 | MAPT (0.59) | MAPTRAB9AKMT2AALDH1A1HTT | |
| SCHEMBL10577075 | 0.71 | NPC1 (0.50) | MAPTRAB9AKMT2AALDH1A1HTT | |
| SCHEMBL1975589 | 0.71 | KDM4E (0.61) | KMT2AL3MBTL1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7659307-B2 | Nonphytotoxic; 4-Bromo-3-methoxy-N-4-[4(trifluoromethyl)phenoxy]phenyl-thiophene-2-carboxamide; 4-[(Allyloxycarbonyl)amino]-3-methoxy-N-4-[4-(trifluoromethyl)phenoxy]phenyl-thiophene-2-carboxamide | BAYER CROPSCIENCE S.A. (FR) | 2010-02-09 | — | — | US | disclosed |
| EP-1363925-B1 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LTD (GB) | 2006-11-15 | — | — | EP | disclosed |
| US-20060205732-A1 | Heterocyclic carboxamides and their use as fungicides | BAYER SAS (FR) | 2006-09-14 | — | — | US | disclosed |
| US-7084163-B2 | Heterocyclic carboxamides and their use as fungicides | BAYER CROPSCIENCE S.A. (FR) | 2006-08-01 | — | — | US | disclosed |
| US-20040152698-A1 | Heterocyclic carboxamides and their use as fungicides | BAYER SAS (FR) | 2004-08-05 | — | — | US | disclosed |
| EP-1425276-A2 | HETEROCYCLIC CARBOXAMIDES AND THEIR USE AS FUNGICIDES | Bayer CropScience S.A. (FR) | 2004-06-09 | — | — | EP | disclosed |
| CN-1492874-A | Macrolide antibiotics | — | 2004-04-28 | — | — | CN | disclosed |
| WO-2003006454-A2 | HETEROCYCLIC CARBOXAMIDES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE S.A. (FR) | 2003-01-23 | — | — | WO | disclosed |
| US-4886546-A | Pyrone-3-carboxamide compounds and herbicidal composition thereof | DAICEL CHEMICAL INDUSTRIES LTD. (JP) | 1989-12-12 | — | — | US | disclosed |
| US-4730061-A | PLANT GROWTH REGULATORS | DAICEL CHEMICAL INDUSTRIES LTD. (JP) | 1988-03-08 | — | — | US | disclosed |
| US-4570003-A | DEACETYLATION OF DEHYDROACETIC ACID USING AQUEOUS SULFURIC ACID SOLUTION; RATIOS | ROHM AND HAAS COMPANY (US) | 1986-02-11 | — | — | US | disclosed |
| EP-0059052-A1 | Process for the preparation of a substituted pyrone | ROHM AND HAAS COMPANY (US) | 1982-09-01 | — | — | EP | disclosed |
| US-4115101-A | PLANT GROWTH REGULATORS, CHEMICAL HYBRIDIZATION AGENTS | ROHM AND HAAS COMPANY (US) | 1978-09-19 | — | — | US | disclosed |
| US-4051142-A | PLANT GROWTH REGULATORS | ROHM AND HAAS COMPANY (US) | 1977-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152698-A1 | Heterocyclic carboxamides and their use as fungicides | CYP1A2, CYP4X1, CYCS | MAPT 4778/4885RAB9A 3290/4885KMT2A 333/4885 |
| US-20060205732-A1 | Heterocyclic carboxamides and their use as fungicides | CYP4X1, CYP1A2, CYCS | MAPT 4693/4885RAB9A 3349/4885KMT2A 358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.