Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | MITF | O75030 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822717 | 0.82 | ALDH1A1 (0.58) | ALDH1A1MAPTRECQLGAACYP3A4 | |
| SCHEMBL10726878 | 0.77 | ALDH1A1 (0.59) | ALDH1A1MAPTSMN1; SMN2MITFLMNA | |
| SCHEMBL4470672 | 0.77 | ALDH1A1 (0.59) | ALDH1A1MAPTSMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL1975474 | 0.76 | ALDH1A1 (0.63) | ALDH1A1MAPTSMN1; SMN2MITFLMNA | |
| SCHEMBL1176806 | 0.76 | ALDH1A1 (0.64) | ALDH1A1MAPTSMN1; SMN2MITFLMNA | |
| SCHEMBL3557080 | 0.76 | MAPT (0.41) | ALDH1A1MAPTSMN1; SMN2LMNAAPAF1 | |
| SCHEMBL6026762 | 0.75 | NR1H2 (0.59) | ALDH1A1MAPTSMN1; SMN2NR1H2NR1H3 | |
| SCHEMBL28444935 | 0.75 | ALDH1A1 (0.48) | ALDH1A1MAPTSMN1; SMN2MITFLMNA | |
| SCHEMBL5190617 | 0.74 | POLB (0.56) | ALDH1A1MAPTSMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL10004069 | 0.73 | ALDH1A1 (0.47) | ALDH1A1MAPTSMN1; SMN2LMNANR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4249027-A | Process for the preparation of 5-substituted resorcinols and related intermediates | CIBA-GEIGY CORPORATION (US) | 1981-02-03 | — | — | US | disclosed |
| US-4020098-A | Process for the preparation of 5-substituted resorcinols and related intermediates | CIBA-GEIGY CORPORATION (US) | 1977-04-26 | — | — | US | disclosed |