Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL28233463 | 0.98 | LMNA (0.46) | LMNAALDH1A1GAAMAPTATM | |
| Hydrochloric Acid SCHEMBL27891676 | 0.98 | LMNA (0.46) | LMNAALDH1A1GAAMAPTATM | |
| SCHEMBL15946989 | 0.82 | HPGD (0.47) | LMNAALDH1A1GAAMAPTATM | |
| Benzene SCHEMBL27730624 | 0.80 | CYP2D6 (0.46) | LMNAALDH1A1MAPTCYP2D6SRC | |
| SCHEMBL28308616 | 0.80 | TSHR (0.50) | LMNAALDH1A1CYP2D6SRCTSHR | |
| SCHEMBL664900 | 0.80 | SRC (0.56) | LMNAALDH1A1MAPTCYP2D6SRC | |
| SCHEMBL5325296 | 0.80 | SRC (0.56) | LMNAALDH1A1MAPTCYP2D6SRC | |
| SCHEMBL9181806 | 0.80 | CYP2D6 (0.50) | LMNACYP2D6SRCTSHRHPGD | |
| SCHEMBL3993198 | 0.79 | SMN1; SMN2 (0.42) | LMNAALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL3993817 | 0.79 | BRD4 (0.61) | LMNACYP2D6TSHRMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110526808-A | A kind of medicine intermediate and preparation method thereof | HENAN RENHUA BIOTECHNOLOGY CO LTD | 2019-12-03 | — | — | CN | claimed |
| CN-209428430-U | It is a kind of to produce the washing kettle used chlorophenyl acetone | 泰州市科研精细化工有限公司 | 2019-09-24 | — | — | CN | claimed |
| CN-106008183-B | The preparation method of ephedrine or pseudoephedrine and ephedrine or pseudoephedrine intermediate | 浙江普洛康裕制药有限公司 | 2019-05-07 | — | — | CN | claimed |
| CN-109705051-A | Tri- substituted oxazoline of 2,4,5- and its synthetic method | 湖南城市学院 | 2019-05-03 | — | — | CN | claimed |
| CN-109503345-A | A kind of washing kettle that improved production uses chlorophenyl acetone | 泰州市科研精细化工有限公司 | 2019-03-22 | — | — | CN | claimed |
| CN-108752229-A | A kind of synthetic method of propanil | 山东润博生物科技有限公司 | 2018-11-06 | — | — | CN | claimed |
| CN-108558787-A | A kind of preparation method of high-efficiency low-toxicity acaricide Hexythiazox | 江苏禾本生化有限公司 | 2018-09-21 | — | — | CN | claimed |
| CN-108410913-A | The method and purposes of carrot tissue or callus asymmetric reduction p- phenylpropyl alcohol ketone class compounds | 杨妮 | 2018-08-17 | — | — | CN | claimed |
| CN-108220348-A | The method of Rice Callus asymmetric reduction p- phenylpropyl alcohol ketone class compounds | 浙江工业大学 | 2018-06-29 | — | — | CN | claimed |
| CN-106632131-A | Hexythiazox and preparation method thereof | 温州大学 | 2017-05-10 | — | — | CN | claimed |
| CN-101585810-B | Preparation method of 5-(4-chlorphenyl)-1-(2, 4-dichlorophenyl) 4- methylpyrazole-3-formic ether | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2011-12-14 | — | — | CN | claimed |
| CN-102260154-A | Preparation method of pharmaceutical intermediate alpha-bromo-p-chloropropiophenone | — | 2011-11-30 | — | — | CN | claimed |
| CN-101805250-A | Preparation method of p-chloropropiophenone | UNIV NANTONG | 2010-08-18 | — | — | CN | claimed |
| CN-101585810-A | Preparation method of 5-(4-chlorphenyl)-1-(2, 4-dichlorophenyl) 4- methylpyrazole-3-formic ether | UNIV EAST CHINA SCIENCE & TECH (CN) | 2009-11-25 | — | — | CN | claimed |
| CN-101565679-A | Rhodotorula cell and method for producing optical active alcohols by asymmetric conversion | UNIV CHINA PHARMA (CN) | 2009-10-28 | — | — | CN | claimed |
| CN-101235016-A | Method for synthesizing fat-reducing medicament rimonabant | TAIZHOU JINZHAO WEIYE FINE CHE (CN) | 2008-08-06 | — | — | CN | claimed |
| WO-2007036948-A1 | NOVEL MERCAPTOBENZIMIDAZOLE SUBSTITUTED BENZOTRIAZOLE UV ABSORBER AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2007-04-05 | — | — | WO | claimed |
| US-20070078266-A1 | Novel mercaptobenzimidazole substituted benzotriazole UV absorber and process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2007-04-05 | — | — | US | claimed |
| US-4923649-A | Pelletizing polymers | PHILLIPS PETROLEUM COMPANY (US) | 1990-05-08 | — | — | US | claimed |
| US-4020059-A | Process for preparing tertiary amines | NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JA) | 1977-04-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078266-A1 | Novel mercaptobenzimidazole substituted benzotriazole UV absorber and process for preparation thereof | SULT1A1, SULT2A1, CYP1A1 | LMNA 2851/4885ALDH1A1 168/4885GAA 3454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.