Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10448400 | 0.81 | TSHR (0.33) | TSHRGAAEPHX1 | |
| SCHEMBL7272503 | 0.77 | TSHR (0.47) | TSHRGAAEPHX1 | |
| SCHEMBL6294190 | 0.77 | TSHR (0.47) | TSHRGAAEPHX1 | |
| SCHEMBL2712968 | 0.75 | TSHR (0.37) | TSHRGAAEPHX1 | |
| SCHEMBL4328796 | 0.75 | TSHR (0.37) | TSHRGAAEPHX1 | |
| SCHEMBL647264 | 0.75 | TSHR (0.37) | TSHRGAAEPHX1 | |
| SCHEMBL9744380 | 0.75 | TSHR (0.37) | TSHRGAAEPHX1 | |
| SCHEMBL9744375 | 0.75 | TSHR (0.37) | TSHRGAAEPHX1 | |
| SCHEMBL14666763 | 0.74 | ADH1B (0.38) | TSHRGAAEPHX1 | |
| Hydrochloric Acid SCHEMBL30546580 | 0.74 | TSHR (0.36) | TSHRGAAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709644-B2 | Process for the enantiomeric enrichment of cis-8-benzyl-7,9-dioxo-2,8-diazabicyclo[4.3.0]nonane | LANXESS DEUTSCHLAND GMBH (DE) | 2010-05-04 | — | — | US | disclosed |
| US-20070213536-A1 | Process for the enantiomeric enrichment of cis-8-benzyl-7,9-dioxo-2,8-diazabicyclo[4.3.0]nonane | LANXESS DEUTSCHLAND GMBH (DE) | 2007-09-13 | — | — | US | disclosed |
| EP-1375501-B1 | Process for enantiomeric enrichment of cis-8-benzyl-7,9-dioxo-2,8-diazabicyclo(4.3.0)nonane using simulated moving bed chromatography | LANXESS DEUTSCHLAND GMBH (DE) | 2005-11-02 | — | — | EP | disclosed |
| US-20040044205-A1 | Process for the enantiomeric enrichment of cis-8-benzyl-7,9-dioxo-2,8-diazabicyclo[4.3.0]nonane | LANXESS DEUTSCHLAND GMBH (DE) | 2004-03-04 | — | — | US | disclosed |
| EP-1375501-A1 | Process for enantiomeric enrichment of cis-8-benzyl-7,9-dioxo-2,8-diazabicyclo(4.3.0)nonane using simulated moving bed chromatography | Bayer Chemicals AG (DE) | 2004-01-02 | — | — | EP | disclosed |
| EP-0379917-B1 | Optically active (meth)acrylic-acid derivatives, their preparation, their polymerisation into optically active polymers and their use | BAYER AG (DE) | 1995-08-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044205-A1 | Process for the enantiomeric enrichment of cis-8-benzyl-7,9-dioxo-2,8-diazabicyclo[4.3.0]nonane | CYP1B1, DECR1, SPIN2B | TSHR 4681/4885GAA 3078/4885EPHX1 669/4885 |
| US-20070213536-A1 | Process for the enantiomeric enrichment of cis-8-benzyl-7,9-dioxo-2,8-diazabicyclo[4.3.0]nonane | CYP1B1, CYP8B1, CCR8 | TSHR 4295/4885GAA 3251/4885EPHX1 624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.