Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 15/20 | 0.40 |
| ▸ | PORCN | Q9H237 | 2/20 | 0.39 |
| ▸ | CD38 | P28907 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3561819 | 1.00 | NOS2 (0.40) | NOS2PORCNCD38 | |
| SCHEMBL3563583 | 0.97 | PORCN (0.42) | NOS2PORCNCD38 | |
| SCHEMBL3560162 | 0.97 | PORCN (0.42) | NOS2PORCNCD38 | |
| SCHEMBL3560159 | 0.97 | PORCN (0.42) | NOS2PORCNCD38 | |
| SCHEMBL3564868 | 0.80 | GAA (0.36) | NOS2CD38 | |
| SCHEMBL3563224 | 0.80 | GAA (0.36) | NOS2CD38 | |
| SCHEMBL3558401 | 0.80 | GAA (0.36) | NOS2CD38 | |
| SCHEMBL3563649 | 0.76 | CHEK1 (0.47) | NOS2PORCNCD38 | |
| SCHEMBL3563642 | 0.76 | CHEK1 (0.47) | NOS2PORCNCD38 | |
| SCHEMBL19704898 | 0.74 | NOS2 (0.57) | NOS2CD38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825256-B2 | Inducible nitric oxide synthase dimerization inhibitors | KALYPSYS, INC. (US) | 2010-11-02 | — | — | US | disclosed |