Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 4/20 | 0.33 |
| ▸ | CD38 | P28907 | 8/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3563224 | 1.00 | GAA (0.36) | GAANOS2CD38SCN9AMEN1 | |
| SCHEMBL3558401 | 1.00 | GAA (0.36) | GAANOS2CD38SCN9AMEN1 | |
| SCHEMBL3629701 | 0.82 | NOS2 (0.43) | NOS2NOS1 | |
| SCHEMBL3622846 | 0.82 | NOS2 (0.43) | NOS2NOS1 | |
| SCHEMBL3560162 | 0.81 | PORCN (0.42) | NOS2CD38KMT2A | |
| SCHEMBL3560159 | 0.81 | PORCN (0.42) | NOS2CD38KMT2A | |
| SCHEMBL3563583 | 0.81 | PORCN (0.42) | NOS2CD38KMT2A | |
| SCHEMBL3561824 | 0.80 | NOS2 (0.40) | NOS2CD38 | |
| SCHEMBL3561819 | 0.80 | NOS2 (0.40) | NOS2CD38 | |
| SCHEMBL3563649 | 0.76 | CHEK1 (0.47) | NOS2CD38MEN1USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825256-B2 | Inducible nitric oxide synthase dimerization inhibitors | KALYPSYS, INC. (US) | 2010-11-02 | — | — | US | disclosed |