Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6760023 | 0.85 | RAB9A (0.41) | MAPK1CYP2C19KMT2AABCB1CHRNB2 | |
| SCHEMBL3074123 | 0.82 | ALDH1A1 (0.43) | ALDH1A1GAAMAPTKDM4EMAPK1 | |
| Maleic Acid SCHEMBL3066099 | 0.80 | LMNA (0.39) | ALDH1A1MAPK1CYP2C19KMT2ASMN1; SMN2 | |
| Bgp-15 SCHEMBL2325445 | 0.79 | ABCB1 (0.46) | KDM4EMAPK1CYP2C19SMN1; SMN2ABCB1 | |
| Bgp-15 SCHEMBL29358886 | 0.79 | ABCB1 (0.46) | KDM4EMAPK1CYP2C19SMN1; SMN2ABCB1 | |
| SCHEMBL3074051 | 0.78 | DRD4 (0.44) | MAPK1CYP2C19KMT2AABCB1MEN1 | |
| Bgp-15 SCHEMBL3067994 | 0.78 | CYP2D6 (0.45) | ALDH1A1GAAKDM4EMAPK1CYP2C19 | |
| Bgp-15 SCHEMBL28351041 | 0.78 | CYP2D6 (0.45) | ALDH1A1GAAKDM4EMAPK1CYP2C19 | |
| Hydrochloric Acid SCHEMBL3066259 | 0.77 | PIK3CB (0.36) | ALDH1A1MAPTCYP2C19SMN1; SMN2ABCB1 | |
| Hydrochloric Acid SCHEMBL9426703 | 0.77 | MAPK1 (0.44) | KDM4EMAPK1CYP2C19SMN1; SMN2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745465-B2 | Method of enhancing cellular production of molecular chaperone, hydroxylamine derivatives useful for enhancing the chaperone production and the preparation thereof | CYTRX CORPORATION (US) | 2010-06-29 | — | — | US | disclosed |