SCHEMBL3563685

SCHEMBL3563685

C=CCn1cnn(-c2ccc(Sc3cccc(C4(C(N)=O)CCOCC4)c3)cc2)c1=O

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 7/20 0.55
PIK3CD O00329 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3563550 0.89 ALOX5 (0.59) ALOX5PIK3CD
SCHEMBL3573121 0.88 ALOX5 (0.56) ALOX5PIK3CD
SCHEMBL3572207 0.87 ALOX5 (0.58) ALOX5PIK3CD
SCHEMBL3576191 0.87 ALOX5 (0.57) ALOX5PIK3CD
SCHEMBL3571691 0.87 ALOX5 (0.56) ALOX5PIK3CD
SCHEMBL3576895 0.86 ALOX5 (0.54) ALOX5PIK3CD
SCHEMBL3566982 0.86 ALOX5 (0.56) ALOX5PIK3CD
SCHEMBL3570620 0.85 ALOX5 (0.37) ALOX5PIK3CD
SCHEMBL3568549 0.84 ALOX5 (0.62) ALOX5PIK3CD
SCHEMBL3571273 0.84 ALOX5 (0.60) ALOX5PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7674811-B2 5-lipoxygenase inhibitors RANBAXY LABORATORIES LIMITED (IN) 2010-03-09 US claimed
US-20080021080-A1 5-LIPOXYGENASE INHIBITORS RANBAXY LABORATORIES LIMITED (IN) 2008-01-24 US claimed
EP-1834953-A1 Tetrahydropyrane derivatives as 5-lipoxygenase inhibitors Ranbaxy Laboratories Limited (IN) 2007-09-19 EP claimed
US-7674811-B2 5-lipoxygenase inhibitors RANBAXY LABORATORIES LIMITED (IN) 2010-03-09 US disclosed
US-20080021080-A1 5-LIPOXYGENASE INHIBITORS RANBAXY LABORATORIES LIMITED (IN) 2008-01-24 US disclosed
EP-1834953-A1 Tetrahydropyrane derivatives as 5-lipoxygenase inhibitors Ranbaxy Laboratories Limited (IN) 2007-09-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080021080-A1 5-LIPOXYGENASE INHIBITORS ALOX5, ALOX15B, ALOX15 ALOX5 1/4885PIK3CD 2405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.