⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2093119 | 0.86 | — | — | |
| SCHEMBL2096722 | 0.84 | NAAA (0.41) | — | |
| SCHEMBL8670495 | 0.84 | ALOX5 (0.43) | — | |
| SCHEMBL1269467 | 0.82 | NAAA (0.43) | — | |
| SCHEMBL16289445 | 0.82 | NAAA (0.43) | — | |
| SCHEMBL16289313 | 0.82 | NAAA (0.43) | — | |
| SCHEMBL357256 | 0.79 | — | — | |
| SCHEMBL6002653 | 0.76 | CETP (0.33) | — | |
| SCHEMBL7341457 | 0.75 | — | — | |
| SCHEMBL983235 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 347 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2670406-B1 | COMBINATION THERAPY WITH INTERFERON BETA AND ANDROGRAPHOLIDES FOR MULTIPLE SCLEROSIS | INNOBIOSCIENCE LLC (US) | 2015-09-02 | — | — | EP | claimed |
| US-9060994-B2 | Combination therapy with interferon and andrographolides for Multiple Sclerosis | Inno Biosciences, S.p.A. (CL) | 2015-06-23 | — | — | US | claimed |
| US-20140301981-A1 | Combination Therapy with Interferon and Andrographolides for Multiple Sclerosis | INNOBIOSCIENCE LLC (US) | 2014-10-09 | — | — | US | claimed |
| EP-1555266-B1 | REMEDIES OR PREVENTIVES FOR URINARY INCONTINENCE AND MORPHINAN DERIVATIVES HAVING NITROGEN-CONTAINING HETEROCYCLIC GROUP | TORAY INDUSTRIES (JP) | 2014-05-21 | — | — | EP | claimed |
| EP-2670406-A1 | COMBINATION THERAPY WITH INTERFERON AND ANDROGRAPHOLIDES FOR MULTIPLE SCLEROSIS | Herbal Powers Corporation (US) | 2013-12-11 | — | — | EP | claimed |
| WO-2013096423-A1 | COMBINATION THERAPY WITH INTERFERON AND ANDROGRAPHOLIDES FOR MULTIPLE SCLEROSIS | Herbal Powers Corporation (US) | 2013-06-27 | — | — | WO | claimed |
| US-7320984-B2 | Remedies or preventives for urinary frequency or urinary incontinence and morphinan derivatives having nitrogen-containing heterocyclic group | TORAY INDUSTRIES, INC. (JP) | 2008-01-22 | — | — | US | claimed |
| US-20060040970-A1 | Remedies or preventives for urinary frequency or urinary incontinence and morphinan derivatives having nitrogen-containing heterocyclic group | TORAY INDUSTRIES, INC. (JP) | 2006-02-23 | — | — | US | claimed |
| EP-1555266-A1 | REMEDIES OR PREVENTIVES FOR URINARY FREQUENCY OR URINARY INCONTINENCE AND MORPHINAN DERIVATIVES HAVING NITROGEN-CONTAINING HETEROCYCLIC GROUP | TORAY INDUSTRIES, INC. (JP) | 2005-07-20 | — | — | EP | claimed |
| EP-1121118-A4 | FORMAMIDES AS THERAPEUTIC AGENTS | GLAXO GROUP LTD (GB) | 2002-09-11 | — | — | EP | claimed |
| EP-1121118-A1 | FORMAMIDES AS THERAPEUTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2001-08-08 | — | — | EP | claimed |
| US-6172064-B1 | METALLOPROTEASE INHIBITOR; ANTIARTHRITIC AGENTS, ANTIDIABETIC AGENTS; ANTITUMOR AGENTS | GLAXO WELLCOME INC. | 2001-01-09 | — | — | US | claimed |
| WO-2000012083-A1 | FORMAMIDES AS THERAPEUTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2000-03-09 | — | — | WO | claimed |
| WO-2000012082-A1 | FORMAMIDE COMPOUNDS AS THERAPEUTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2000-03-09 | — | — | WO | claimed |
| WO-2024056101-A1 | LINKER FOR ANTIBODY-DRUG CONJUGATE AND USE THEREOF | 上海君实生物医药科技股份有限公司 | 2024-03-21 | — | — | WO | disclosed |
| US-20230099694-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2023-03-30 | — | — | US | disclosed |
| US-20220409573-A1 | Hippocampus Regeneration And Memory Recovery | INNOBIOSCIENCE, LLC (US) | 2022-12-29 | — | — | US | disclosed |
| US-4775692-A | ANTILIPEMIC, ANTICOAGULANT, HYPOTENSIVE, ANTISECRETORY AND ANTIULCER AGENT | TORAY INDUSTRIES, INC. (JP) | 1988-10-04 | — | — | US | disclosed |
| EP-0274064-A2 | 2,5,6,7-Tetranor-18,18,19,19-tetradehydro-4,8-inter-m-phenylene PGI2 derivatives | TORAY INDUSTRIES, INC. (JP) | 1988-07-13 | — | — | EP | disclosed |
| EP-0232776-A2 | 2,5,6,7-tetranor-4,8-inter-m-phenylene PGI2 derivatives | TORAY INDUSTRIES, INC. (JP) | 1987-08-19 | — | — | EP | disclosed |