Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2096694 | 0.85 | NAAA (0.39) | CETPALOX5LTA4HNAAA | |
| SCHEMBL2092743 | 0.80 | CETP (0.40) | CETPALOX5LTA4HSLC1A3SLC1A2 | |
| SCHEMBL2092244 | 0.79 | — | — | |
| SCHEMBL9548860 | 0.77 | CETP (0.38) | CETPALOX5LTA4HSLC1A3SLC1A2 | |
| SCHEMBL356407 | 0.76 | — | — | |
| SCHEMBL10205487 | 0.75 | ALDH1A1 (0.39) | CETPLTA4HSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2092246 | 0.75 | — | — | |
| SCHEMBL8670495 | 0.75 | ALOX5 (0.43) | CETPALOX5LTA4HSLC1A3SLC1A2 | |
| SCHEMBL2093119 | 0.72 | — | — | |
| SCHEMBL2092738 | 0.72 | CETP (0.36) | CETPALOX5LTA4HSLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |