Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 2/20 | 0.34 |
| ▸ | COPS5 | Q92905 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | CCR1 | P32246 | 3/20 | 0.32 |
| ▸ | CCR8 | P51685 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | CCR5 | P51681 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9277705 | 0.75 | SGMS2 (0.36) | PSMD14COPS5CYP2A6ALDH1A1CCR1 | |
| SCHEMBL15638227 | 0.73 | FLT3 (0.44) | CYP2A6ALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL20181538 | 0.72 | TLR8 (0.50) | CYP2A6ALDH1A1CCR1CCR8KDM4E | |
| SCHEMBL128666 | 0.72 | ALDH1A1 (0.42) | PSMD14COPS5CYP2A6ALDH1A1CCR1 | |
| SCHEMBL2624387 | 0.69 | CCR1 (0.37) | PSMD14COPS5CYP2A6ALDH1A1CCR1 | |
| SCHEMBL15966361 | 0.68 | HTT (0.42) | ALDH1A1CCR1CCR8KDM4ECCR5 | |
| SCHEMBL16901678 | 0.68 | ALDH1A1 (0.42) | ALDH1A1CCR1CCR8KDM4ECCR5 | |
| SCHEMBL18660657 | 0.68 | HTT (0.38) | PSMD14COPS5ALDH1A1CCR1CCR8 | |
| SCHEMBL3574183 | 0.68 | PTGES (0.51) | ALDH1A1KDM4EALOX15TSHRNPC1 | |
| SCHEMBL15935208 | 0.68 | ALDH1A1 (0.35) | PSMD14COPS5CYP2A6ALDH1A1CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7674907-B2 | Furanopyridine derivatives and methods of use | AMGEN INC. (US) | 2010-03-09 | — | — | US | disclosed |
| US-20060046977-A1 | Furanopyridine derivatives and methods of use | AMGEN INC. | 2006-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060046977-A1 | Furanopyridine derivatives and methods of use | LCK, NFATC1, MINK1 | PSMD14 3340/4885COPS5 3853/4885CYP2A6 3621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.