SCHEMBL3565646

SCHEMBL3565646

CC(C)(C)OC(=O)N1CCC(CCCOc2ccc(C#N)c(F)c2)CC1

nearest known ligand 0.71

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 16/20 0.71
TRPV4 Q9HBA0 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31753322 0.95 GPR119 (0.64) GPR119TRPV4
SCHEMBL31752283 0.91 GPR119 (0.58) GPR119TRPV4
SCHEMBL7251887 0.85 HRH2 (0.52) GPR119
SCHEMBL15109863 0.85 GPR119 (0.58) GPR119
SCHEMBL1576133 0.85 GPR119 (0.75) GPR119
SCHEMBL1574984 0.85 GPR119 (0.75) GPR119
SCHEMBL2340177 0.84 GPR119 (0.71) GPR119
SCHEMBL1576050 0.84 GPR119 (0.71) GPR119
SCHEMBL1575619 0.84 GPR119 (0.74) GPR119
SCHEMBL1575291 0.84 GPR119 (0.74) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025262297-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 DARK BLUE THERAPEUTICS LTD (GB) 2025-12-26 WO disclosed
US-8993603-B2 Pharmaceutical composition and method using antifungal agent in combination TOYAMA CHEMICAL CO., LTD. (JP) 2015-03-31 US disclosed
US-8993603-B2 Pharmaceutical composition and method using antifungal agent in combination TOYAMA CHEMICAL CO., LTD. (JP) 2015-03-31 US disclosed
US-8993603-B2 Pharmaceutical composition and method using antifungal agent in combination TOYAMA CHEMICAL CO., LTD. (JP) 2015-03-31 US disclosed
EP-1767526-B1 ARYLAMIDINE DERIVATIVE, SALT THEREOF AND ANTIFUNGAL CONTAINING THESE TOYAMA CHEMICAL CO LTD (JP) 2012-10-24 EP disclosed
EP-1767526-B1 ARYLAMIDINE DERIVATIVE, SALT THEREOF AND ANTIFUNGAL CONTAINING THESE TOYAMA CHEMICAL CO LTD (JP) 2012-10-24 EP disclosed
US-7700623-B2 Arylamidine derivative, salt thereof, and antifungal containing these TOYAMA CHEMICAL CO., LTD. (JP) 2010-04-20 US disclosed
US-7700623-B2 Arylamidine derivative, salt thereof, and antifungal containing these TOYAMA CHEMICAL CO., LTD. (JP) 2010-04-20 US disclosed
US-7700623-B2 Arylamidine derivative, salt thereof, and antifungal containing these TOYAMA CHEMICAL CO., LTD. (JP) 2010-04-20 US disclosed
US-20090087480-A1 PHARMACEUTICAL COMPOSITION AND METHOD USING ANTIFUNGAL AGENT IN COMBINATION TOYAMA CHEMICAL CO., LTD. (JP) 2009-04-02 US disclosed
US-20090087480-A1 PHARMACEUTICAL COMPOSITION AND METHOD USING ANTIFUNGAL AGENT IN COMBINATION TOYAMA CHEMICAL CO., LTD. (JP) 2009-04-02 US disclosed
US-20090087480-A1 PHARMACEUTICAL COMPOSITION AND METHOD USING ANTIFUNGAL AGENT IN COMBINATION TOYAMA CHEMICAL CO., LTD. (JP) 2009-04-02 US disclosed
US-20080319016-A1 Novel Arylamidine Derivative, Salt Thereof, and Antifungal Containing These TOYAMA CHEMICAL CO., LTD. (JP) 2008-12-25 US disclosed
US-20080319016-A1 Novel Arylamidine Derivative, Salt Thereof, and Antifungal Containing These TOYAMA CHEMICAL CO., LTD. (JP) 2008-12-25 US disclosed
US-20080319016-A1 Novel Arylamidine Derivative, Salt Thereof, and Antifungal Containing These TOYAMA CHEMICAL CO., LTD. (JP) 2008-12-25 US disclosed
EP-1867332-A1 PHARMACEUTICAL COMPOSITION AND METHOD USING ANTIFUNGAL AGENT IN COMBINATION TOYAMA CHEMICAL CO., LTD. (JP) 2007-12-19 EP disclosed
EP-1767526-A1 NOVEL ARYLAMIDINE DERIVATIVE, SALT THEREOF, AND ANTIFUNGAL CONTAINING THESE TOYAMA CHEMICAL CO., LTD. (JP) 2007-03-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090087480-A1 PHARMACEUTICAL COMPOSITION AND METHOD USING ANTIFUNGAL AGENT IN COMBINATION PIK3C3, ARSA, ACR GPR119 823/4885TRPV4 4684/4885
US-20080319016-A1 Novel Arylamidine Derivative, Salt Thereof, and Antifungal Containing These NAT1, ERG28, SLC7A1 GPR119 295/4885TRPV4 3521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.