SCHEMBL3566191

SCHEMBL3566191

Cc1cc(-c2ccc(Cl)c(C)c2)nc(-n2cnc(-c3ccc(S(=O)(=O)NC(C)(C)C)s3)c2)n1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 4/20 0.34
FEN1 P39748 4/20 0.34
MAPT P10636 3/20 0.34
TP53 P04637 1/20 0.33
RXFP1 Q9HBX9 2/20 0.32
PRNP P04156 1/20 0.32
KDM4E B2RXH2 2/20 0.32
ABL1 P00519 1/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
PPARG P37231 1/20 0.32
KMT2A Q03164 1/20 0.32
NCOA2 Q15596 1/20 0.32
PTGS1 P23219 2/20 0.31
PTGS2 P35354 2/20 0.31
BRD4 O60885 1/20 0.30
BRD2 P25440 1/20 0.30
BRD3 Q15059 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3570196 0.94 ABL1 (0.35) ALOX5APFEN1MAPTRXFP1PRNP
SCHEMBL3562478 0.90 GABRA1 (0.36) ALOX5APFEN1MAPTTP53RXFP1
SCHEMBL3562459 0.86 CA1 (0.41) MAPTRXFP1KDM4EMEN1LMNA
SCHEMBL3562462 0.85 P2RY14 (0.38) ALOX5APFEN1MAPT
SCHEMBL3563495 0.83 JAK2 (0.38) MAPTTP53KDM4EMEN1LMNA
SCHEMBL3562984 0.83 MAPT (0.35) ALOX5APFEN1MAPTKDM4EABL1
SCHEMBL3568647 0.82 ABL1 (0.34) ALOX5APFEN1ABL1
SCHEMBL3559343 0.80 KDM4E (0.34) ALOX5APFEN1MAPTRXFP1KDM4E
SCHEMBL3559394 0.80 PFKFB4 (0.39) ALOX5APFEN1MAPTTP53RXFP1
SCHEMBL3563607 0.80 CA12 (0.46) MAPTRXFP1KDM4EABL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115955980-A Variable charge joint 思进公司 2023-04-11 CN disclosed
CN-108713032-A Resin combination 纳美仕有限公司 2018-10-26 CN disclosed
CN-105934452-B Thermosetting resin composition, cured product thereof, and electric/electronic component 昭和电工株式会社 2018-10-26 CN disclosed
CN-108347943-A HEPATITIS B CORE PROTEIN MODULATORS 组装生物科学股份有限公司 2018-07-31 CN disclosed
US-20150126734-A1 PROCESS FOR PREPARATION OF N,N-DI SUBSTITUTED CARBOXAMIDES DIRECTOR GENERAL, DEFENCE RESEARCH & DEVELOPMENT ORGNISATION (IN) 2015-05-07 US disclosed
CN-102791750-B Ethylene-alpha-olefin copolymer and molded article SUMITOMO CHEMICAL CO.,LTD. (JP) 2014-10-29 CN disclosed
CN-104114531-A Process for preparation of n,n-di substituted carboxamides DIRECTOR GENERAL DEFENCE RES AND DEV ORGANISATION 2014-10-22 CN disclosed
CN-103391950-A Ethylene-alfa-olefin copolymer and molded article SUMITOMO CHEMICAL CO 2013-11-13 CN disclosed
CN-103154070-A Interlayer filler composition for three-dimensional integrated circuit, coating liquid, and method for producing three-dimensional integrated circuit MITSUBISHI CHEM CORP 2013-06-12 CN disclosed
WO-2013065059-A1 PROCESS FOR PREPARATION OF N,N-DI SUBSTITUTED CARBOXAMIDES DIRECTOR GENERAL, DEFENCE RESEARCH & DEVELOPMENT ORGANISATION (IN) 2013-05-10 WO disclosed
CN-1277828-C Piperzine devivs. HOFFMANN LA ROCHE (CH) 2006-10-04 CN disclosed
CN-1247723-C Conductive adhesive and assembled structural body by use of said adhesive MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 2006-03-29 CN disclosed
CN-1671667-A Quinoline derivatives and their use as mycobacterial inhibitors JANSSEN PHARMACEUTICA NV (BE) 2005-09-21 CN disclosed
CN-1575290-A Pyrimidine derivatives and pharmaceutical compositions containing that compounds EISAI CO LTD (JP) 2005-02-02 CN disclosed
CN-1543452-A 1, 4-disubstituted benzene insecticides FMC 2004-11-03 CN disclosed
CN-1452622-A Piperzine devivs. HOFFMANN LA ROCHE (CH) 2003-10-29 CN disclosed
CN-1447638-A Welding method and welded component NIPPON ELECTRICAL EIFOMIMITSU (JP) 2003-10-08 CN disclosed
CN-1344256-A (Hetero) aryl-bicyclic heteroaryl derivatives, their prepn. and their use as protease inhibitors AXYS PHARM INC (US) 2002-04-10 CN disclosed
CN-1340584-A Conductive adhesive and assembled structural body by use of said adhesive MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 2002-03-20 CN disclosed
CN-1224989-A Process for promoting chemical adhesion of legend inks using ultra-violet light GEN ELECTRIC (US) 1999-08-04 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150126734-A1 PROCESS FOR PREPARATION OF N,N-DI SUBSTITUTED CARBOXAMIDES CPS1, NAAA, OTC ALOX5AP 2550/4885FEN1 4079/4885MAPT 3961/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.