Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3558069 | 1.00 | DPP4 (0.68) | DPP4CHRM1 | |
| SCHEMBL637078 | 1.00 | DPP4 (0.68) | DPP4CHRM1 | |
| SCHEMBL637440 | 1.00 | DPP4 (0.68) | DPP4CHRM1 | |
| SCHEMBL638967 | 1.00 | DPP4 (0.68) | DPP4CHRM1 | |
| SCHEMBL3562854 | 1.00 | DPP4 (0.68) | DPP4CHRM1 | |
| SCHEMBL1542117 | 0.93 | DPP4 (0.69) | DPP4CHRM1 | |
| SCHEMBL638295 | 0.93 | DPP4 (0.69) | DPP4CHRM1 | |
| SCHEMBL557205 | 0.93 | DPP4 (0.69) | DPP4CHRM1 | |
| SCHEMBL638460 | 0.91 | DPP4 (0.75) | DPP4CHRM1 | |
| SCHEMBL639184 | 0.91 | DPP4 (0.75) | DPP4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7838529-B2 | Xanthine derivates, their preparation and their use in pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-11-23 | — | — | US | disclosed |
| US-20090131432-A1 | XANTHINE DERIVATES, THEIR PREPARATION AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2009-05-21 | — | — | US | disclosed |
| US-7495005-B2 | Xanthine derivatives, their preparation and their use in pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2009-02-24 | — | — | US | disclosed |
| US-20040166125-A1 | Xanthine derivatives, their preparation and their use in pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040166125-A1 | Xanthine derivatives, their preparation and their use in pharmaceutical compositions | XDH, CALCRL, CALCA | DPP4 55/4885CHRM1 117/4885 |
| US-20090131432-A1 | XANTHINE DERIVATES, THEIR PREPARATION AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS | XDH, CALCRL, GPR119 | DPP4 68/4885CHRM1 54/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.