Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 4/20 | 0.42 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1828237 | 0.90 | MMP13 (0.43) | P2RX7ALDH1A1EGFRENPP2ENPP1 | |
| SCHEMBL1823208 | 0.89 | P2RX7 (0.43) | P2RX7ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL1826243 | 0.86 | CNR1 (0.46) | P2RX7ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL1823084 | 0.86 | P2RX7 (0.45) | P2RX7ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL13345184 | 0.85 | P2RX7 (0.45) | P2RX7ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL1825145 | 0.85 | P2RX7 (0.45) | P2RX7ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL1823302 | 0.84 | P2RX7 (0.46) | P2RX7ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL1823199 | 0.84 | P2RX7 (0.46) | P2RX7ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL1822763 | 0.84 | P2RX7 (0.55) | P2RX7ALDH1A1TSHRMMP13 | |
| SCHEMBL1826175 | 0.83 | P2RX7 (0.45) | P2RX7ALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7714157-B2 | Process for preparing a biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-05-11 | — | — | US | disclosed |
| US-20070270603-A1 | Process for preparing a biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED | 2007-11-22 | — | — | US | disclosed |
| US-7271280-B2 | Process for preparing a biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-09-18 | — | — | US | disclosed |
| EP-1481967-A1 | PROCESS FOR THE PREPARATION OF BIARYL COMPOUNDS | Sumitomo Chemical Company, Limited (JP) | 2004-12-01 | — | — | EP | disclosed |
| US-20040158093-A1 | Process for preparing a biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040158093-A1 | Process for preparing a biaryl compound | CYP1B1, REL, CYP2F1 | P2RX7 3606/4885ALDH1A1 1099/4885KMT2A 1068/4885 |
| US-20070270603-A1 | Process for preparing a biaryl compound | CYP4A11, CYP4B1, CYP51A1 | P2RX7 2747/4885ALDH1A1 1440/4885KMT2A 1084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.