Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 19/20 | 0.39 |
| ▸ | NOS1 | P29475 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3566047 | 0.91 | NOS2 (0.39) | NOS2NOS1 | |
| SCHEMBL3570485 | 0.76 | NOS2 (0.67) | NOS2NOS1 | |
| SCHEMBL3562901 | 0.75 | NOS2 (0.41) | NOS2NOS1 | |
| SCHEMBL3569290 | 0.73 | NOS2 (0.57) | NOS2NOS1TSHR | |
| SCHEMBL3556345 | 0.71 | NOS2 (0.55) | NOS2NOS1 | |
| SCHEMBL3564163 | 0.71 | NOS2 (0.40) | NOS2NOS1 | |
| SCHEMBL3564776 | 0.71 | NOS2 (0.36) | NOS2NOS1KDM4ETSHRMAPK1 | |
| SCHEMBL3570719 | 0.71 | NOS2 (0.60) | NOS2NOS1 | |
| Hydrochloric Acid SCHEMBL3557590 | 0.70 | NOS2 (0.42) | NOS2NOS1 | |
| SCHEMBL3559323 | 0.70 | NOS2 (0.39) | NOS2NOS1KDM4ETSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825256-B2 | Inducible nitric oxide synthase dimerization inhibitors | KALYPSYS, INC. (US) | 2010-11-02 | — | — | US | disclosed |