Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 12/20 | 0.57 |
| ▸ | NOS1 | P29475 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 5/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3562883 | 0.84 | NOS2 (0.39) | NOS2NOS1POLBNPC1TSHR | |
| SCHEMBL3571989 | 0.82 | NOS2 (0.53) | NOS2NOS1POLBNPC1TSHR | |
| SCHEMBL3570486 | 0.73 | NOS2 (0.39) | NOS2NOS1TSHR | |
| SCHEMBL3559827 | 0.73 | NOS2 (0.44) | NOS2NOS1PDE5ATBXAS1PDE3B | |
| SCHEMBL3569287 | 0.73 | NOS2 (1.00) | NOS2NOS1 | |
| SCHEMBL3566047 | 0.72 | NOS2 (0.39) | NOS2NOS1 | |
| SCHEMBL3563614 | 0.72 | NOS2 (0.51) | NOS2NOS1NPC1TSHRHSD17B10 | |
| SCHEMBL3571983 | 0.71 | NOS2 (0.73) | NOS2NOS1 | |
| SCHEMBL3556345 | 0.71 | NOS2 (0.55) | NOS2NOS1 | |
| SCHEMBL3561919 | 0.71 | NOS2 (0.54) | NOS2NOS1NPC1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825256-B2 | Inducible nitric oxide synthase dimerization inhibitors | KALYPSYS, INC. (US) | 2010-11-02 | — | — | US | disclosed |