SCHEMBL357194

SCHEMBL357194

O=S(=O)(O)C(F)(F)C(F)F.[KH]

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL321209 0.97 ALDH1A1 (0.39) ALDH1A1L3MBTL1TSHRTDP1
Hydrochloric Acid SCHEMBL11271021 0.94 ALDH1A1 (0.38) ALDH1A1L3MBTL1TSHRTDP1
Fluoride SCHEMBL27565651 0.94 ALDH1A1 (0.38) ALDH1A1L3MBTL1TSHRTDP1
Water SCHEMBL9500989 0.94 ALDH1A1 (0.38) ALDH1A1L3MBTL1TSHRTDP1
SCHEMBL1865841 0.94 ALDH1A1 (0.38) ALDH1A1L3MBTL1TSHRTDP1
Ammonia Solution, Strong SCHEMBL28334670 0.94 ALDH1A1 (0.38) ALDH1A1L3MBTL1TSHRTDP1
SCHEMBL576102 0.87 ALDH1A1 (0.33) ALDH1A1L3MBTL1
SCHEMBL3297818 0.85 ALDH1A1 (0.32) ALDH1A1L3MBTL1
1,3-Propanediol SCHEMBL575506 0.83 ATR (0.32) ALDH1A1L3MBTL1
1,4-Butanediol SCHEMBL576160 0.83 ATR (0.32) ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7947770-B2 blend of polycarbonate resin prepared from diphenylcarbonate and 2,2-bis(4-hydroxyphenyl)propane; polytetrafluoroethylene antidrip agent; tetrafluoroalkylsulfonate or hexafluorodialkylsulfonimide salt of Na, K, Cs, Li or a pyridium, pydridazinium, phosphonium, ammonium etc.; protective devices E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-05-24 US claimed
US-20080221241-A1 Flame Retardant Polycarbonate Compositions E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-09-11 US claimed
US-9376379-B2 Process for the synthesis of tetrafluoroethanesulfonic acid SRF LIMITED (IN) 2016-06-28 US disclosed
US-20150259281-A1 PROCESS FOR THE SYNTHESIS OF TETRAFLUOROETHANESULFONIC ACID SRF LIMITED (IN) 2015-09-17 US disclosed
EP-2118194-B1 FLAME RETARDANT POLYCARBONATE COMPOSITIONS DU PONT (US) 2014-12-03 EP disclosed
US-20140286849-A1 Mixtures of Ammonia and Ionic Liquids E. I. DU PONT DE NEMOURS AND COMPANY (US) 2014-09-25 US disclosed
US-8715521-B2 Absorption cycle utilizing ionic liquid as working fluid E I DU PONT DE NEMOURS AND COMPANY (US) 2014-05-06 US disclosed
US-8707720-B2 Hybrid vapor compression-absorption cycle E I DU PONT DE NEMOURS AND COMPANY (US) 2014-04-29 US disclosed
WO-2014020614-A2 PROCESS FOR THE SYNTHESIS OF TETRAFLUOROETHANESULFONIC ACID SRF LIMITED (IN) 2014-02-06 WO disclosed
US-8628644-B2 Utilizing ionic liquids for hydrofluorocarbon separation E I DU PONT NEMOURS AND COMPANY (US) 2014-01-14 US disclosed
US-8568608-B2 Vapor compression cycle utilizing ionic liquid as compressor lubricant E I DU PONT DE NEMOURS AND COMPANY (US) 2013-10-29 US disclosed
US-20070066854-A1 Preparation of polytrimethylene ether glycol and copolymers thereof THE CHEMOURS COMPANY FC, LLC 2007-03-22 US disclosed
US-20070066852-A1 Preparation of poly(tetramethylene) glycol THE CHEMOURS COMPANY FC, LLC 2007-03-22 US disclosed
US-20070066822-A1 Ionic liquids THE CHEMOURS COMPANY FC, LLC 2007-03-22 US disclosed
US-20070066853-A1 Preparation of poly(tetramethylene) glycol E. I. DU PONT DE NEMOURS AND COMPANY 2007-03-22 US disclosed
US-20070066834-A1 Ionic liquids E. I. DU PONT DE NEMOURS AND COMPANY 2007-03-22 US disclosed
US-20070019708-A1 Hybrid vapor compression-absorption cycle E. I. DU PONT DE NEMOURS AND COMPANY 2007-01-25 US disclosed
WO-2006124776-A2 HYBRID VAPOR COMPRESSION-ABSORPTION CYCLE E.I. DU PONT DE NEMOURS AND COMPANY (US) 2006-11-23 WO disclosed
US-20060197053-A1 Absorption cycle utilizing ionic liquid as working fluid E. I. DU PONT DE NEMOURS AND COMPANY 2006-09-07 US disclosed
WO-2006084262-A1 ABSORPTION CYCLE UTILIZING IONIC LIQUID AS WORKING FLUID E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-08-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070066853-A1 Preparation of poly(tetramethylene) glycol PARG, PUF60, TPR ALDH1A1 2896/4885L3MBTL1 2316/4885TSHR 3729/4885
US-20070066834-A1 Ionic liquids NUP205, PML, AQP4 ALDH1A1 3482/4885L3MBTL1 3533/4885TSHR 3674/4885
US-20070066854-A1 Preparation of polytrimethylene ether glycol and copolymers thereof PARG, PTGES3, PGD ALDH1A1 840/4885L3MBTL1 3248/4885TSHR 4703/4885
US-20070066822-A1 Ionic liquids AFF2, AFF1, ZYX ALDH1A1 3728/4885L3MBTL1 857/4885TSHR 445/4885
US-20070066852-A1 Preparation of poly(tetramethylene) glycol PARG, PUF60, TPR ALDH1A1 2896/4885L3MBTL1 2316/4885TSHR 3729/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.