SCHEMBL357236

SCHEMBL357236

C[N+](C)(C)CCOS(=O)(=O)C(F)(F)C(F)F

nearest known ligand 0.31

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM5 P08912 3/20 0.31
CHRM1 P11229 3/20 0.31
CHRM3 P20309 3/20 0.31
CHRM2 P08172 2/20 0.31
CHRM4 P08173 2/20 0.31
HTR1A P08908 2/20 0.31
CHRNB2 P17787 2/20 0.31
CHRNA7 P36544 2/20 0.31
CHRNA4 P43681 2/20 0.31
SLC6A4 P31645 1/20 0.31
ADRA2A P08913 1/20 0.31
ADRA1A P35348 1/20 0.31
PGR P06401 1/20 0.31
TBXA2R P21731 1/20 0.31
CHRNB4 P30926 1/20 0.31
CHRNA3 P32297 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CHRNA10 Q9GZZ6 1/20 0.31
CHRNA9 Q9UGM1 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3785101 0.80 CA2 (0.42) CHRM5CHRM1CHRM3CHRM2CHRM4
SCHEMBL575505 0.78 CA1 (0.32) LMNATSHR
SCHEMBL576159 0.78 CA1 (0.37) LMNATSHR
SCHEMBL4369370 0.76 CA2 (0.45) BLMLMNATSHR
SCHEMBL28031252 0.68 CHRM5 (0.42) CHRM5CHRM1CHRM3CHRM2CHRM4
Choline SCHEMBL27857086 0.67 MEN1 (0.43) LMNA
SCHEMBL575267 0.67
SCHEMBL15527811 0.66 TSHR (0.55) CHRM5CHRM1CHRM3CHRM2CHRM4
SCHEMBL21148404 0.66 USP2 (0.32) TSHR
Choline SCHEMBL357235 0.66 MEN1 (0.41) BLMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2414476-A1 IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS E. I. du Pont de Nemours and Company (US) 2012-02-08 EP claimed
WO-2010117836-A1 IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-10-14 WO claimed
US-20120011886-A1 IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS E. I. DU PONT DE NEMOURS AND COMPANY 2012-01-19 US disclosed