SCHEMBL357361

SCHEMBL357361

c1ccc(Oc2nc3ccccc3s2)cc1

nearest known ligand 0.71

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.71
CYP1A2 P05177 1/20 0.71
CYP3A4 P08684 1/20 0.71
CYP2D6 P10635 1/20 0.71
CYP2C19 P33261 1/20 0.71
LTA4H P09960 14/20 0.57
KCNH2 Q12809 2/20 0.55
NPC1 O15118 1/20 0.53
MAPK1 P28482 1/20 0.53
RAB9A P51151 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
PTGS1 P23219 3/20 0.50
PTGS2 P35354 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11471037 0.94 CYP1A2 (0.73) SMN1; SMN2CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL6736271 0.88 CYP1A2 (0.60) SMN1; SMN2CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL8736766 0.86 SMN1; SMN2 (0.64) SMN1; SMN2CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL8683976 0.86 CYP1A2 (0.68) SMN1; SMN2CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL8683981 0.86 CYP1A2 (0.68) SMN1; SMN2CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL18612334 0.86 SMN1; SMN2 (0.64) SMN1; SMN2CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL4465201 0.86 CYP1A2 (0.60) SMN1; SMN2CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL3491330 0.84 CYP1A2 (1.00) SMN1; SMN2CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL5496753 0.82 SMN1; SMN2 (0.52) SMN1; SMN2CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL22224242 0.82 LTA4H (0.62) SMN1; SMN2CYP1A2CYP3A4CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1008 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111808142-A Organic phosphorus luminescent compound and preparation method and application thereof 奥来德(上海)光电材料科技有限公司 2020-10-23 CN claimed
US-20260150572-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2026-05-28 US disclosed
CN-122071493-A Organic electroluminescent material and device 环球展览公司 2026-05-22 CN disclosed
CN-122071498-A Organic electroluminescent material and device 环球展览公司 2026-05-22 CN disclosed
CN-122071496-A Organic electroluminescent material and device 环球展览公司 2026-05-22 CN disclosed
CN-122071494-A Organic electroluminescent material and device 环球展览公司 2026-05-22 CN disclosed
CN-122071495-A Organic electroluminescent material and device 环球展览公司 2026-05-22 CN disclosed
CN-122071497-A Organic electroluminescent material and device 环球展览公司 2026-05-22 CN disclosed
CN-122071492-A Organic electroluminescent material and device 环球展览公司 2026-05-22 CN disclosed
US-20260143961-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2026-05-21 US disclosed
EP-1056725-A4 INHIBITION OF RAF KINASE USING ARYL AND HETEROARYL SUBSTITUTED HETEROCYCLIC UREAS BAYER AG (US) 2001-02-07 EP disclosed
EP-1047418-A4 INHIBITION OF RAF KINASE USING SUBSTITUTED HETEROCYCLIC UREAS BAYER AG (US) 2001-02-07 EP disclosed
EP-1056725-A1 INHIBITION OF RAF KINASE USING ARYL AND HETEROARYL SUBSTITUTED HETEROCYCLIC UREAS Bayer Corporation (US) 2000-12-06 EP disclosed
EP-1047418-A1 INHIBITION OF RAF KINASE USING SUBSTITUTED HETEROCYCLIC UREAS Bayer Corporation (US) 2000-11-02 EP disclosed
EP-1043995-A1 INHIBITION OF p38 KINASE ACTIVITY USING ARYL AND HETEROARYL SUBSTITUTED HETEROCYCLIC UREAS Bayer Corporation (US) 2000-10-18 EP disclosed
EP-1041982-A1 INHIBITION OF p38 KINASE ACTIVITY USING SUBSTITUTED HETEROCYCLIC UREAS Bayer Corporation (US) 2000-10-11 EP disclosed
WO-1999032106-A1 INHIBITION OF RAF KINASE USING SUBSTITUTED HETEROCYCLIC UREAS BAYER CORPORATION (US) 1999-07-01 WO disclosed
WO-1999032110-A1 INHIBITION OF p38 KINASE ACTIVITY USING ARYL AND HETEROARYL SUBSTITUTED HETEROCYCLIC UREAS BAYER CORPORATION (US) 1999-07-01 WO disclosed
WO-1999032455-A1 INHIBITION OF RAF KINASE USING ARYL AND HETEROARYL SUBSTITUTED HETEROCYCLIC UREAS BAYER CORPORATION (US) 1999-07-01 WO disclosed
WO-1999032111-A1 INHIBITION OF p38 KINASE ACTIVITY USING SUBSTITUTED HETEROCYCLIC UREAS BAYER CORPORATION (US) 1999-07-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260143961-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, GLRB, GLRA1 SMN1; SMN2 3608/4885CYP1A2 3011/4885CYP3A4 2616/4885
US-20260150572-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, OPRD1, CHRND SMN1; SMN2 2564/4885CYP1A2 3471/4885CYP3A4 1847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.