SCHEMBL357391

SCHEMBL357391

CC(O)(F)CF

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL477969 1.00
SCHEMBL477720 1.00
SCHEMBL765922 0.78
SCHEMBL533226 0.78
SCHEMBL4495282 0.75
SCHEMBL1450906 0.75
Hydrochloric Acid SCHEMBL28282660 0.75
SCHEMBL4447966 0.75
Methyl Alcohol SCHEMBL365291 0.75
SCHEMBL9476213 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0120242-B1 PROCESS FOR COATING A SUBSTRATE WITH POLYIMIDE International Business Machines Corporation (US) 1987-01-07 EP claimed
WO-2024053650-A1 COMPOUND HAVING INHIBITORY ACTIVITY AGAINST DIACYLGLYCEROL KINASE α AND/OR ζ, AND PHARMACEUTICAL USE THEREOF 小野薬品工業株式会社 2024-03-14 WO disclosed
CN-116947890-A Tricyclic compound of WEE1 inhibitor, and preparation method and application thereof 星希尔生物科技(上海)有限公司 2023-10-27 CN disclosed
CN-116836157-A Oxadiazole derivative and preparation method and application thereof 星希尔生物科技(上海)有限公司 2023-10-03 CN disclosed
WO-2023179366-A1 OXADIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF 星希尔生物科技(上海)有限公司 2023-09-28 WO disclosed
US-20230014137-A1 COMPOUND HAVING LYSOPHOSPHATIDIC ACID RECEPTOR AGONIST ACTIVITY AND PHARMACEUTICAL USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2023-01-19 US disclosed
WO-2021107125-A1 COMPOUND HAVING LYSOPHOSPHATIDIC ACID RECEPTOR AGONISTIC ACTIVITY AND PHARMACEUTICAL USE OF SAID COMPOUND 小野薬品工業株式会社 2021-06-03 WO disclosed
US-10336718-B2 Method for industrial production of optically active fluoroalkyl ethylene oxide CENTRAL GLASS COMPANY, LIMITED (JP) 2019-07-02 US disclosed
US-20180312483-A1 Method for Industrial Production of Optically Active Fluoroalkyl Ethylene Oxide CENTRAL GLASS COMPANY, LIMITED (JP) 2018-11-01 US disclosed
WO-2015091931-A1 OXINDOLE DERIVATIVES CARRYING A PIPERIDYL-SUBSTITUTED AZETIDINYL SUBSTITUENT AND USE THEREOF FOR TREATING VASOPRESSINE-RELATED DISEASES AbbVie Deutschland GmbH & Co. KG (DE) 2015-06-25 WO disclosed
US-20120015975-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-19 US disclosed
US-7956041-B2 antidiabetic mixture contains an inhibitor of renal glucose reabsorption and a hypoglycemic agent; controlling blood glucose level; tolbutamide, chlorpropamide, glibenclamide, glipizide, glimepiride, and gliclazide; metformin, phenformin and buformin; repaglinide, nateglinide and mitiglinide AJINOMOTO CO., INC. (JP) 2011-06-07 US disclosed
US-7592386-B2 Dual cure hydrotalcite containing fluoropolymer compositions 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-09-22 US disclosed
US-7402630-B2 Curing compositions for fluoropolymers 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-07-22 US disclosed
US-20080116603-A1 DUAL CURE HYDROTALCITE CONTAINING FLUOROPOLYMER COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY 2008-05-22 US disclosed
US-20050143424-A1 Prophylactic and therapeutic agent of diabetes mellitus AJINOMOTO CO. INC (JP) 2005-06-30 US disclosed
EP-1500403-A1 PREVENTIVE/REMEDY FOR DIABETES Ajinomoto Co., Inc. (JP) 2005-01-26 EP disclosed
US-6593319-B1 Novel 17,20-dihydrofusidic acid derivatives are used in pharmaceutical compositions for the treatment of infections, in particular in topical compositions for the treatment of skin or eye infections. LEO PHARMACEUTICAL PRODUCTS, LTD. A/S (DK) 2003-07-15 US disclosed
EP-0042991-B1 CARBONYL-AMINO-URETHANES AND HERBICIDAL AND FUNGICIDAL COMPOSITIONS CONTAINING THEM BASF Aktiengesellschaft (DE) 1983-07-13 EP disclosed
EP-0042991-A1 Carbonyl-amino-urethanes and herbicidal and fungicidal compositions containing them BASF Aktiengesellschaft (DE) 1982-01-06 EP disclosed