SCHEMBL533226

SCHEMBL533226

CC(C)(O)CF

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28282660 0.96
SCHEMBL765922 0.82
SCHEMBL1450906 0.78
SCHEMBL357391 0.78
SCHEMBL477969 0.78
SCHEMBL477720 0.78
SCHEMBL9560224 0.75 ALDH1A1 (0.37)
Hydrochloric Acid SCHEMBL23577695 0.75
SCHEMBL3382392 0.75
SCHEMBL27679024 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115015236-A Reusable time temperature indicator and preparation method thereof 四川大学 2022-09-06 CN claimed
JP-4234333-A None JP disclosed
WO-2025089370-A1 COMPOUNDS AS CSF1R INHIBITORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2025-05-01 WO disclosed
US-20250136606-A1 MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE CARAWAY THERAPEUTICS, INC. (US) 2025-05-01 US disclosed
EP-4408850-A1 MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE Caraway Therapeutics, Inc. (US) 2024-08-07 EP disclosed
CN-118317963-A TRPML modulators, compositions thereof, and methods of use 卡拉韦治疗公司 2024-07-09 CN disclosed
US-20240199692-A1 POLYPEPTIDE HAVING MMP2-INHIBITORY EFFECT TAISHO PHARMACEUTICAL CO., LTD. (JP) 2024-06-20 US disclosed
CN-111918717-B Olefin polymerization activator 陶氏环球技术有限责任公司 2024-04-09 CN disclosed
US-11858885-B2 Cellulosic complex and applications thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2024-01-02 US disclosed
CN-116018136-A Hypoxia-inducible factor prolyl hydroxylase inhibitors for the treatment of aging-related disorders 百爱及生物医药公司 2023-04-25 CN disclosed
US-5672723-A SELECTIVE HYDROLYSIS OR ALCOHOLYSIS OF A MIXTURE OF 1-ACYL-1-ALKYLHYDRAZINE AND 1-ACYL-2-ALKYLHYDRAZINE USING AN ACID CATALYST TO OBTAIN AN ACID OR ESTER AND THE STABLE 1-ACYL-2-ALKYLHYRAZINE NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1997-09-30 US disclosed
CN-1147813-A Novel compounds, their synthesis and therapeutic use GILEAD SCIENCES INC (US) 1997-04-16 CN disclosed
EP-0639558-B1 Process for preparation of 1-acyl-2-substituted-hydrazines NIPPON KAYAKU KK (JP) 1996-10-23 EP disclosed
US-5559256-A Aminediol protease inhibitors E. R. SQUIBB & SONS, INC. (US) 1996-09-24 US disclosed
EP-0639558-A1 Process for preparation of 1-acyl-2-substituted-hydrazines Nippon Kayaku Kabushiki Kaisha (JP) 1995-02-22 EP disclosed
EP-0580402-A2 Aminediol protease inhibitors E.R. SQUIBB & SONS, INC. (US) 1994-01-26 EP disclosed
US-5276218-A Reacting an epoxide with sodium or potassium hydrogen fluoride under pressure BAYER AKTIENGESELLSCHAFT (DE) 1994-01-04 US disclosed
JP-H04234333-A PRODUCTION OF BETA-FLUOROALCOHOL BAYER AG 1992-08-24 JP disclosed
EP-0468308-A2 Process for the preparation of beta-fluorinated alcohols BAYER AG (DE) 1992-01-29 EP disclosed
EP-0464539-A2 Method for preparation of beta-fluoro-tert. alkyl amine hydrochlorides and beta-fluoro-tert. alkylamides BAYER AG (DE) 1992-01-08 EP disclosed