Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 10/20 | 0.34 |
| ▸ | LIPC | P11150 | 3/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 3/20 | 0.31 |
| ▸ | LPL | P06858 | 2/20 | 0.31 |
| ▸ | GPR6 | P46095 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3582142 | 0.91 | CYP3A4 (0.37) | CYP3A4KCNH2LIPGLIPCPIM1 | |
| SCHEMBL3590136 | 0.90 | CYP3A4 (0.35) | CYP3A4PIM1PIM3PIM2SMN1; SMN2 | |
| SCHEMBL3577931 | 0.82 | KCNH2 (0.33) | CYP3A4KCNH2LIPGLIPCDRD2 | |
| SCHEMBL482753 | 0.80 | CYP3A4 (0.72) | CYP3A4KCNH2 | |
| SCHEMBL3590072 | 0.79 | CYP3A4 (0.57) | CYP3A4KCNH2 | |
| SCHEMBL3578342 | 0.77 | MEN1 (0.35) | SMN1; SMN2DRD2 | |
| SCHEMBL2078715 | 0.77 | CYP3A4 (0.70) | CYP3A4KCNH2 | |
| SCHEMBL2078716 | 0.77 | CYP3A4 (0.70) | CYP3A4KCNH2 | |
| SCHEMBL2081996 | 0.72 | CYP3A4 (0.58) | CYP3A4KCNH2LIPGLPL | |
| SCHEMBL2081994 | 0.72 | CYP3A4 (0.58) | CYP3A4KCNH2LIPGLPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100069435-A1 | METHOD OF SELECTIVELY INTRODUCING AMINO SUBSTITUENT | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2010-03-18 | — | — | US | disclosed |
| US-7626029-B2 | Into a difluorobenzoic acid, for producting quinolonecarboxylic acid serving as synthetic antibacterial agent, medicament, agricultural chemical, or veterinary drug; ionic liquid solvents | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-12-01 | — | — | US | disclosed |
| US-20060122396-A1 | Method of selectively introducing amino substituent | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-06-08 | — | — | US | disclosed |
| EP-1634879-A1 | METHOD OF SELECTIVELY INTRODUCING AMINO SUBSTITUENT | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-03-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122396-A1 | Method of selectively introducing amino substituent | ASNS, NQO2, DDC | CYP3A4 300/4885KCNH2 2642/4885LIPG 4760/4885 |
| US-20100069435-A1 | METHOD OF SELECTIVELY INTRODUCING AMINO SUBSTITUENT | ASNS, DDC, NQO2 | CYP3A4 140/4885KCNH2 2726/4885LIPG 4802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.