Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TOP1 | P11387 | 5/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | CLK2 | P49760 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LIPC | P11150 | 1/20 | 0.30 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3575973 | 0.82 | CYP3A4 (0.42) | KCNH2DRD2CYP3A4LIPCLIPG | |
| SCHEMBL3590136 | 0.78 | CYP3A4 (0.35) | DRD2DRD3CYP3A4KDM4EALDH1A1 | |
| SCHEMBL3578342 | 0.78 | MEN1 (0.35) | DRD2DRD3POLBKDM4EALDH1A1 | |
| SCHEMBL3582142 | 0.78 | CYP3A4 (0.37) | KCNH2DRD2DRD3CYP3A4LIPC | |
| SCHEMBL20549812 | 0.73 | KCNH2 (0.48) | KCNH2SCN5APOLBKDM4EALDH1A1 | |
| SCHEMBL17494347 | 0.71 | SCN5A (0.69) | KCNH2SCN5A | |
| SCHEMBL20549374 | 0.71 | SCN5A (0.50) | KCNH2SCN5APOLBKDM4EPRKD3 | |
| SCHEMBL20549384 | 0.70 | KCNH2 (0.51) | KCNH2SCN5APOLBKDM4EALDH1A1 | |
| SCHEMBL20549424 | 0.70 | SCN5A (0.49) | KCNH2SCN5AKDM4EALDH1A1HPGD | |
| SCHEMBL20549490 | 0.69 | KCNH2 (0.49) | KCNH2SCN5APOLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100069435-A1 | METHOD OF SELECTIVELY INTRODUCING AMINO SUBSTITUENT | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2010-03-18 | — | — | US | disclosed |
| US-7626029-B2 | Into a difluorobenzoic acid, for producting quinolonecarboxylic acid serving as synthetic antibacterial agent, medicament, agricultural chemical, or veterinary drug; ionic liquid solvents | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-12-01 | — | — | US | disclosed |
| US-20060122396-A1 | Method of selectively introducing amino substituent | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-06-08 | — | — | US | disclosed |
| EP-1634879-A1 | METHOD OF SELECTIVELY INTRODUCING AMINO SUBSTITUENT | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-03-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122396-A1 | Method of selectively introducing amino substituent | ASNS, NQO2, DDC | KCNH2 2642/4885DRD2 1605/4885DRD3 2221/4885 |
| US-20100069435-A1 | METHOD OF SELECTIVELY INTRODUCING AMINO SUBSTITUENT | ASNS, DDC, NQO2 | KCNH2 2726/4885DRD2 1982/4885DRD3 2052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.