Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 17/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.74 |
| ▸ | CASP1 | P29466 | 2/20 | 0.74 |
| ▸ | CASP7 | P55210 | 2/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10158686 | 0.85 | ALDH1A1 (1.00) | ALDH1A1HSD17B10CASP1CASP7MAPK1 | |
| SCHEMBL9073375 | 0.83 | ALDH1A1 (0.81) | ALDH1A1HSD17B10CASP1CASP7MAPK1 | |
| SCHEMBL27032826 | 0.83 | ALDH1A1 (0.72) | ALDH1A1HSD17B10CASP1CASP7MAPK1 | |
| SCHEMBL26993612 | 0.82 | ALDH1A1 (0.71) | ALDH1A1HSD17B10CASP1CASP7MAPK1 | |
| SCHEMBL27238846 | 0.81 | ALDH1A1 (0.61) | ALDH1A1HSD17B10CASP1CASP7MAPK1 | |
| SCHEMBL29744372 | 0.79 | ALDH1A1 (0.68) | ALDH1A1HSD17B10CASP1CASP7MAPK1 | |
| SCHEMBL15367241 | 0.79 | ALDH1A1 (0.68) | ALDH1A1HSD17B10CASP1CASP7MAPK1 | |
| SCHEMBL3059418 | 0.77 | ALDH1A1 (0.72) | ALDH1A1HSD17B10CASP1CASP7MAPK1 | |
| SCHEMBL5738983 | 0.77 | ALDH1A1 (0.59) | ALDH1A1HSD17B10CASP1CASP7MAPK1 | |
| SCHEMBL3273745 | 0.77 | ALDH1A1 (0.59) | ALDH1A1HSD17B10CASP1CASP7MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100081650-A1 | Antimicrobial Compounds | AXTEN JEFFREY MICHAEL | 2010-04-01 | — | — | US | disclosed |
| US-7622481-B2 | Antibacterial compounds | GLAXO GROUP LIMITED (GB) | 2009-11-24 | — | — | US | disclosed |
| EP-1537123-B1 | AMINO-SUBSTITUTED CYCLOHEXANE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | GLAXO GROUP LTD (GB) | 2009-04-29 | — | — | EP | disclosed |
| US-20060189604-A1 | Compounds | GLAXO GROUP LIMITED (GB) | 2006-08-24 | — | — | US | disclosed |
| EP-1537123-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004002992-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2004-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189604-A1 | Compounds | ELANE, PIGS, SDHA | ALDH1A1 2290/4885HSD17B10 931/4885CASP1 67/4885 |
| US-20100081650-A1 | Antimicrobial Compounds | ELANE, NISCH, PIGS | ALDH1A1 2504/4885HSD17B10 1307/4885CASP1 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.