Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3576770 | 0.85 | MT-CO2 (0.49) | L3MBTL1MAPK1ALDH1A1LMNAMAPT | |
| SCHEMBL3583119 | 0.83 | HDAC2 (0.48) | KDM4CSORT1NAMPTL3MBTL1TRPV1 | |
| SCHEMBL3586286 | 0.77 | HDAC6 (0.53) | ALDH1A1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL3576438 | 0.76 | KDM4E (0.49) | MAPK1ALDH1A1LMNAHTTKMT2A | |
| SCHEMBL3572770 | 0.76 | TSHR (0.66) | NAMPTL3MBTL1ALDH1A1LMNAMAPT | |
| SCHEMBL3583284 | 0.75 | MAPK14 (0.54) | SORT1LSSMAPK1ALDH1A1KMT2A | |
| SCHEMBL3572599 | 0.74 | MT-CO2 (0.45) | L3MBTL1ALDH1A1LMNAMAPTHTT | |
| SCHEMBL16676648 | 0.73 | KDM4C (0.71) | KDM4CALDH1A1 | |
| SCHEMBL3580598 | 0.73 | MT-CO2 (0.47) | LSSALDH1A1LMNAHTTKMT2A | |
| SCHEMBL3576343 | 0.72 | HDAC1 (0.52) | L3MBTL1LSSLMNAHTTROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | disclosed |
| US-20070219261-A1 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219261-A1 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | AADAT, AAAS, AADAC | KDM4C 2531/4885SORT1 4547/4885NAMPT 547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.