Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3582620 | 0.83 | HDAC6 (0.55) | HDAC6KMT2APDPK1KDM4EHPGD | |
| SCHEMBL3576770 | 0.83 | MT-CO2 (0.49) | HDAC6MT-CO2KMT2AMAPTMEN1 | |
| SCHEMBL3576350 | 0.77 | KDM4C (0.47) | HDAC6KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL3571438 | 0.75 | HPGD (0.64) | HDAC6KMT2AMAPTKDM4EHPGD | |
| SCHEMBL3576343 | 0.74 | HDAC1 (0.52) | HDAC6LMNASMN1; SMN2 | |
| SCHEMBL27863532 | 0.74 | CHIA (0.53) | KMT2AMAPTMEN1KDM4ENPSR1 | |
| SCHEMBL16676654 | 0.73 | LMNA (0.55) | KMT2AMAPTMEN1KDM4ENPSR1 | |
| SCHEMBL3572770 | 0.73 | TSHR (0.66) | HDAC6KMT2AMAPTMEN1HPGD | |
| SCHEMBL3576438 | 0.73 | KDM4E (0.49) | HDAC6MT-CO2KMT2AMEN1KDM4E | |
| SCHEMBL3580598 | 0.73 | MT-CO2 (0.47) | MT-CO2KMT2AMEN1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | disclosed |
| US-20070219261-A1 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219261-A1 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | AADAT, AAAS, AADAC | HDAC6 1130/4885MT-CO2 858/4885KMT2A 341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.