SCHEMBL35777

SCHEMBL35777

COC(=O)C(C)=CC=Cc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.60
ALDH1A1 P00352 4/20 0.51
KDM4E B2RXH2 2/20 0.51
POLB P06746 1/20 0.49
HPGD P15428 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2C9 P11712 1/20 0.48
GLA P06280 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
GAA P10253 1/20 0.47
HDAC3 O15379 1/20 0.46
HDAC4 P56524 1/20 0.46
HDAC1 Q13547 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC2 Q92769 1/20 0.46
HDAC10 Q969S8 1/20 0.46
HDAC11 Q96DB2 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
HDAC9 Q9UKV0 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8991908 1.00 LMNA (0.60) LMNAALDH1A1KDM4EPOLBHPGD
SCHEMBL10623293 0.93 LMNA (0.54) LMNAALDH1A1KDM4EPOLBHPGD
SCHEMBL10623290 0.93 LMNA (0.54) LMNAALDH1A1KDM4EPOLBHPGD
SCHEMBL1172155 0.92 LMNA (0.53) LMNAALDH1A1KDM4EPOLBHPGD
SCHEMBL4355988 0.88 GAA (0.51) LMNAALDH1A1KDM4EPOLBHPGD
SCHEMBL435341 0.88 GAA (0.51) LMNAALDH1A1KDM4EPOLBHPGD
SCHEMBL5875902 0.87 LMNA (0.49) LMNAALDH1A1KDM4EPOLBHPGD
SCHEMBL4535017 0.86 LMNA (0.48) LMNAALDH1A1KDM4EPOLBHPGD
SCHEMBL8043549 0.85 TYR (0.53) LMNAALDH1A1KDM4ECYP2C9MAOB
SCHEMBL9143755 0.85 LMNA (0.52) LMNAALDH1A1KDM4EPOLBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3142 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12636733-B2 Systems and methods for formation of continuous channels within transparent materials Avava, Inc. (US) 2026-05-26 US claimed
US-12636831-B2 Substrates and associated materials for additive manufacturing ALIGN TECHNOLOGY, INC. (US) 2026-05-26 US claimed
US-12631861-B2 Light redirecting prism, a redirecting prismatic wall and a solar panel incorporating the same BANGOLAE BALAJI LAKSHMIKANTH (IN) 2026-05-19 US claimed
WO-2026100441-A1 CELL CULTURE KIT, METHOD FOR PRODUCING CELL CULTURE BODY, AND CELL CULTURE BODY ACCOMMODATED IN CONTAINER セントラル硝子株式会社 2026-05-15 WO claimed
CN-122011402-A PGA resin edge grafting modified graphene, composition, preparation method and application thereof, biodegradable polyester material, application thereof and temporary plugging ball 中国石油化工股份有限公司 2026-05-12 CN claimed
EP-3856696-B1 COMPOSITION COMPRISING SCATTERING PARTICLES TRINSEO EUROPE GMBH (CH) 2026-04-29 EP claimed
US-20260109833-A1 METHOD OF RECOVERING FLAME RETARDANT FROM STYRENIC POLYMER WASTE POLYSTYVERT INC. (CA) 2026-04-23 US claimed
EP-4713388-A1 METHOD OF RECOVERING FLAME RETARDANT FROM STYRENIC POLYMER WASTE Polystyvert Inc. (CA) 2026-03-25 EP claimed
US-12565571-B2 Composition comprising scattering particles TRINSEO EUROPE GMBH (CH) 2026-03-03 US claimed
EP-4676717-A1 METHODS AND DEVICES FOR ADDITIVE MANUFACTURING Align Technology, Inc. (US) 2026-01-14 EP claimed
EP-0469925-B1 Forming web for lining a rigid container GRACE W R & CO (US) 1996-05-29 EP claimed
US-5436280-A Free radical catalysts for polymerization of monomers EDISON POLYMER INNOVATION CORP. (US) 1995-07-25 US claimed
EP-0596704-A1 Electrostatic dissipative polymer blends GENERAL ELECTRIC COMPANY (US) 1994-05-11 EP claimed
US-4908288-A Charge generation and charge transport layers on conductive substrate, both layers contain same polymer binder, the molecular weight of the binder in the charge generation layer being two to six times that of charge transport layer binder CANON KABUSHIKI KAISHA (JP) 1990-03-13 US claimed
US-4857574-A SMOOTH AND GLOSSY FILM AKZO NV (NL) 1989-08-15 US claimed
EP-0172589-B1 DISPERSION OF ADDITION (CO)POLYMERS IN AN ORGANIC LIQUID AKZO N.V. (NL) 1988-11-23 EP claimed
US-4743643-A GRAFTING (METHY)STYRENE ONTO BUTADIENE POLYMER, PEROXIDE INITIATOR, COATING AKZO NV (NL) 1988-05-10 US claimed
US-4737232-A Process for depositing and crystallizing a thin layer of organic material by means of a beam of energy FLICSTEIN JEAN (FR) 1988-04-12 US claimed
EP-0172589-A1 Dispersion of addition (co)polymers in an organic liquid AKZO N.V. (NL) 1986-02-26 EP claimed
US-4220699-A Method for producing a large number of copies by means of copying apparatus RICOH CO., LTD. (JP) 1980-09-02 US claimed